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使用定制CAD/CAM植入物对蝶眶脑膜瘤进行单步切除及眼眶重建

Single-Step Resection of Sphenoorbital Meningiomas and Orbital Reconstruction Using Customized CAD/CAM Implants.

作者信息

Goertz Lukas, Stavrinou Pantelis, Stranjalis George, Timmer Marco, Goldbrunner Roland, Krischek Boris

机构信息

Center for Neurosurgery, University Hospital of Cologne, Cologne, Germany.

Department of Neurosurgery, University of Athens, Evangelismos Hospital, Athens, Greece.

出版信息

J Neurol Surg B Skull Base. 2020 Apr;81(2):142-148. doi: 10.1055/s-0039-1681044. Epub 2019 Mar 1.

DOI:10.1055/s-0039-1681044
PMID:32206532
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7082166/
Abstract

Computer-aided design and manufacturing (CAD/CAM) implants are fabricated based on volumetric analysis of computed tomography (CT) scans and are routinely used for the reconstruction of orbital fractures. We present three cases of patients with sphenoorbital meningiomas that underwent tumor resection, orbital decompression, and orbital reconstruction with patient specific porous titanium or acrylic implants in a single procedure.  The extent of bone resection of the sphenoorbital meningiomas was planned in a virtual three-dimensional (3D) environment using preoperative thin-layer CT data. The anatomy of the orbital wall in the resection area was reconstructed by superimposing the contralateral unaffected orbit and by using the information of the neighboring bony structures. The customized implants and a corresponding craniotomy template were designed in the desired size and shape by the manufacturer.  All patients presented with a sphenoorbital meningioma and exophthalmos. After osteoclastic craniotomy with the drilling template, orbital decompression was performed. Implant fitting was tight in two cases and could be easily fixated with miniplates and screws. In the third patient, a reoperation was necessary for additional bone resection, as well as drilling and repositioning of the implant. The postoperative CT scans showed an accurate reconstruction of the orbital wall. After surgery, exophthalmos was substantially reduced and a satisfying cosmetic result could be finally achieved in all patients.  The concept of preoperative 3D virtual treatment planning and single-step orbital reconstruction with CAD/CAM implants after tumor resection involving the orbit is well feasible and can lead to good cosmetic results.

摘要

计算机辅助设计与制造(CAD/CAM)植入物是基于计算机断层扫描(CT)的容积分析制造的,常用于眼眶骨折的重建。我们报告了3例蝶眶脑膜瘤患者,他们在同一次手术中接受了肿瘤切除、眼眶减压,并使用定制的多孔钛或丙烯酸植入物进行眼眶重建。

利用术前薄层CT数据,在虚拟三维(3D)环境中规划蝶眶脑膜瘤的骨切除范围。通过叠加对侧未受影响的眼眶并利用相邻骨结构的信息,重建切除区域眼眶壁的解剖结构。制造商按所需尺寸和形状设计定制植入物和相应的开颅模板。

所有患者均表现为蝶眶脑膜瘤和眼球突出。使用钻孔模板进行破骨性开颅术后,进行眼眶减压。2例患者植入物贴合紧密,可轻松用微型钢板和螺钉固定。第3例患者需要再次手术,以进行额外的骨切除以及植入物的钻孔和重新定位。术后CT扫描显示眼眶壁重建准确。术后,眼球突出明显减轻,所有患者最终均获得了满意的美容效果。

术前3D虚拟治疗计划以及在涉及眼眶的肿瘤切除后使用CAD/CAM植入物进行单步眼眶重建的概念是切实可行的,并且可以带来良好的美容效果。

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本文引用的文献

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One-step CAD/CAM titanium cranioplasty after drilling template-assisted resection of intraosseous skull base meningioma: technical note.钻孔模板辅助切除骨内型颅底脑膜瘤后一步法计算机辅助设计/计算机辅助制造钛颅骨修补术:技术说明
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A prospective multicenter study to compare the precision of posttraumatic internal orbital reconstruction with standard preformed and individualized orbital implants.一项前瞻性多中心研究,比较创伤后眼眶内重建使用标准预制眼眶植入物和个体化眼眶植入物的精确度。
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