Barakos J A, Dillon W P, Chew W M
Department of Neuroradiology, University of California, San Francisco Medical Center 94143.
Radiology. 1991 Apr;179(1):191-8. doi: 10.1148/radiology.179.1.2006277.
The high signal intensity of fat on T1-weighted magnetic resonance images has limited the utility of gadopentetate dimeglumine in imaging of the extracranial head and neck. Enhancing lesions may be obscured either by proximity to fat or by chemical misregistration artifact. The authors evaluated the role of a gadolinium-enhanced fat suppression imaging technique in the detection of extracranial head and neck abnormalities in 29 patients. These studies were directly compared with conventional pre- and postcontrast T1- and T2-weighted SE sequences. In detecting and defining the extent of abnormalities, fat-suppressed images were superior to non-fat-suppressed gadolinium-enhanced T1-weighted images in the majority of cases (22 of 27 [81%]). Fat-suppressed images were particularly beneficial in the detection of perineural spread of tumor as well as in defining lesions situated within or adjacent to fat-containing areas such as the base of the skull. These findings demonstrate that fat suppression techniques in combination with gadolinium enhancement are of value in extracranial head and neck imaging and should replace conventional postcontrast T1-weighted SE imaging.
脂肪在T1加权磁共振图像上的高信号强度限制了钆喷酸葡胺在颅外头颈部成像中的应用。强化病变可能会因靠近脂肪或化学位移伪影而被掩盖。作者评估了钆增强脂肪抑制成像技术在29例患者颅外头颈部异常检测中的作用。这些研究直接与传统的对比剂前和对比剂后T1加权和T2加权SE序列进行了比较。在检测和确定异常范围方面，在大多数病例（27例中的22例[81%]）中，脂肪抑制图像优于未进行脂肪抑制的钆增强T1加权图像。脂肪抑制图像在检测肿瘤的神经周围扩散以及确定位于含脂肪区域（如颅底）内或附近的病变方面特别有用。这些发现表明，脂肪抑制技术与钆增强相结合在颅外头颈部成像中具有价值，应取代传统的对比剂后T1加权SE成像。
