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[突尼斯阿丽亚娜地区乳腺钼靶筛查项目中检测出的乳腺癌的管理]

[Management of breast cancer detected by a mammography program in the Ariana area of Tunisia].

作者信息

Chelli D, Dimassi K, Zaanouni E, Sfar E, Ben Aissa R, Bouchlaka A, Ben Hmida A, Chelli H, Gueddana N, Chennoufi M B

机构信息

Service A du centre de maternité Tunis.

出版信息

Tunis Med. 2009 Jul;87(7):471-4.

Abstract

OBJECTIVE

To report the epidemiological and anatomoclinical features of breast cancers referred to a department of gynecology from the screening program of l'Ariana state in Tunisia.

MATERIAL AND METHODS

A longitudinal retrospective Study was done over a period of 4 years (2004-2006 ) at the unit "A" gynecology department of the maternity of Tunis. We collected all the cases with histologically confirmed breast cancer diagnosed within the mammography screening program of l'Ariana state, referred to our unit for treatment.

RESULTS

10 patients with histologically confirmed breast cancer were collected during the study period, treated at our unit. Mean age of patients was of 48.8 years. Clinical examination was initially negative in 50% of cases. Mean clinical tumor size was 18 mm, while invasive ductual carcinoma represents the most frequent histological type. One patient (10%) had histological axillary involvement. Conservative surgery was performed for 8 (80%) of the 10 patients.

CONCLUSION

This pilot study of mammography screening confined to a Tunisian state, precludes to the future profile of BC In Tunisia, showing that an early diagnosis can lead to a dramatic reduction of mean clinical tumor size, less histological poor prognostic features, more conservative surgery and a slight improvement of survival. A structured extended screening program must be installed to achieve these goals but requires an important financial and human investment.

摘要

目的

报告从突尼斯阿里亚纳省筛查项目转诊至妇科的乳腺癌的流行病学及解剖临床特征。

材料与方法

在突尼斯市妇产医院“A”妇科病房进行了一项为期4年(2004 - 2006年)的纵向回顾性研究。我们收集了所有在阿里亚纳省乳腺钼靶筛查项目中确诊、并转诊至我们科室接受治疗的组织学确诊乳腺癌病例。

结果

研究期间共收集了10例在我们科室接受治疗的组织学确诊乳腺癌患者。患者的平均年龄为48.8岁。50%的病例初诊时临床检查为阴性。临床肿瘤平均大小为18毫米,浸润性导管癌是最常见的组织学类型。1例患者(10%)有组织学腋窝受累。10例患者中有8例(80%)接受了保乳手术。

结论

这项仅限于突尼斯一个省的乳腺钼靶筛查试点研究,为突尼斯未来乳腺癌的情况提供了参考,表明早期诊断可显著降低临床肿瘤平均大小,减少组织学不良预后特征,增加保乳手术,并略微提高生存率。必须建立一个结构化的扩展筛查项目来实现这些目标,但这需要大量的资金和人力投入。

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