Clinica Goldman of Plastic Surgery, Porto Alegre, Brazil.
Int J Dermatol. 2009 Nov;48(11):1228-32. doi: 10.1111/j.1365-4632.2008.04007.x.
Lipoma is the most common benign mesenchymal tumor composed of mature fat cells. The standard treatment for lipoma is excision. Many treatments have been described in order to minimize the scars produced by surgical excision. The treatment of lipoma using a subdermal laser produces an effective disruption of fat cells and results in a small scar.
To evaluate the efficacy of subcutaneous intralesional application of a pulsed Nd:YAG laser as an option for the treatment of lipoma.
From January 2001 to November 2007, 20 patients (11 women and nine men) with lipomas were treated using a subdermal, pulsed, 1064-nm Nd:YAG laser. After laser treatment, the oily solution, the product of laser action, was removed with a 2-mm cannula using a negative pressure of 350 mmHg. Histology and cytology of the treated tissue were used to analyze the effects of the laser on the fat cells. Ultrasound was performed in some subjects before and after laser treatment.
Subdermal lipoma treatment using a 1064-nm Nd:YAG laser resulted in complete or almost complete removal of the tumor in 100% of patients. Four partial relapses were observed that were treated successfully by the same procedure. Adverse effects were mild and temporary. The combination of a 1064-nm Nd:YAG laser and removal of the cell debris by a suction cannula presented an effective therapeutic option for patients with lipoma.
The treatment of lipoma using a 1064-nm Nd:YAG laser is a minor invasive procedure which does not result in large scars. Laser treatment is an effective and safe option for cellular disruption.
脂肪瘤是最常见的良性间叶组织肿瘤，由成熟的脂肪细胞组成。脂肪瘤的标准治疗方法是切除。为了尽量减少手术切除产生的疤痕，已经描述了许多治疗方法。使用皮下激光治疗脂肪瘤可有效破坏脂肪细胞，并产生小疤痕。
评估皮内应用脉冲 Nd:YAG 激光治疗脂肪瘤的疗效。
2001 年 1 月至 2007 年 11 月，20 例（11 名女性和 9 名男性）脂肪瘤患者接受了皮下单脉冲 1064nm Nd:YAG 激光治疗。激光治疗后，使用 2mm 套管和 350mmHg 的负压抽吸去除激光作用产生的油性溶液。对治疗组织进行组织学和细胞学分析，以评估激光对脂肪细胞的作用。部分患者在激光治疗前后进行了超声检查。
皮下单发脂肪瘤应用 1064nm Nd:YAG 激光治疗，100%的患者肿瘤完全或几乎完全消除。观察到 4 例部分复发，均采用相同方法成功治疗。不良反应轻微且短暂。1064nmNd:YAG 激光联合细胞碎片抽吸的联合治疗为脂肪瘤患者提供了有效的治疗选择。
使用 1064nmNd:YAG 激光治疗脂肪瘤是一种微创程序，不会产生大的疤痕。激光治疗是一种有效且安全的细胞破坏方法。
