渴望洞察。
Itching for insight.
机构信息
Genomics Institute of the Novartis Research Foundation, San Diego, CA 92121, USA.
出版信息
Cell. 2009 Dec 24;139(7):1224-6. doi: 10.1016/j.cell.2009.12.012.
PMID:20064368
Abstract
The itch sensation results from the excitation of primary sensory nerve endings in the skin, but the underlying molecular mechanisms are not completely understood. Liu et al. (2009) now report that some members of the Mrgpr class of G protein-coupled receptors mediate the itch caused by the antimalarial drug chloroquine.
摘要
瘙痒感是由皮肤内初级感觉神经末梢的兴奋引起的，但其中的潜在分子机制尚未完全阐明。刘等人（2009 年）现在报告称，G 蛋白偶联受体 Mrgpr 类的某些成员介导抗疟药物氯喹引起的瘙痒。
Zotero 插件