文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

TLR2 观察脂蛋白。

TLR2 looks at lipoproteins.

机构信息

Division of Dermatology, UCLA School of Medicine, Los Angeles, CA 90095, USA.

出版信息

Immunity. 2009 Dec 18;31(6):847-9. doi: 10.1016/j.immuni.2009.11.008.

DOI:10.1016/j.immuni.2009.11.008
PMID:20064441
Abstract

Toll-like receptors (TLRs) have evolved to recognize lipoproteins from diverse species of bacteria. In this issue of Immunity, Kang et al. (2009) provide insight into the mechanisms by which TLR2-TLR6 heterodimers recognize diacylated liporoteins, whereas TLR2-TLR1 heterodimers recognize triacylated lipopeptides.

摘要

Toll 样受体（TLRs）进化以识别来自不同种类细菌的脂蛋白。在本期《免疫》中，Kang 等人（2009）阐述了 TLR2-TLR6 异二聚体识别双酰化脂蛋白，而 TLR2-TLR1 异二聚体识别三酰化脂肽的机制。

相似文献

[1]
TLR2 looks at lipoproteins.

Immunity. 2009-12-18

[2]
Triacylated lipoproteins derived from Mycoplasma pneumoniae activate nuclear factor-kappaB through toll-like receptors 1 and 2.

Immunology. 2007-8

[3]
Recognition of lipopeptide patterns by Toll-like receptor 2-Toll-like receptor 6 heterodimer.

Immunity. 2009-12-18

[4]
Recognition of lipopeptides by Toll-like receptors.

J Endotoxin Res. 2002

[5]
Toll-like receptor 6-independent signaling by diacylated lipopeptides.

Eur J Immunol. 2005-1

[6]
CD14 directly binds to triacylated lipopeptides and facilitates recognition of the lipopeptides by the receptor complex of Toll-like receptors 2 and 1 without binding to the complex.

Cell Microbiol. 2006-12

[7]
Genomic variants of TLR1--it takes (TLR-)two to tango.

Eur J Immunol. 2007-8

[8]
Heterodimerization of TLR2 with TLR1 or TLR6 expands the ligand spectrum but does not lead to differential signaling.

J Leukoc Biol. 2008-3

[9]
Pegylated bisacycloxypropylcysteine, a diacylated lipopeptide ligand of TLR6, plays a host-protective role against experimental Leishmania major infection.

J Immunol. 2014-9-5

[10]
Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide.

Cell. 2007-9-21

引用本文的文献

[1]
Decoding Mycoplasma Nucleases: Biological Functions and Pathogenesis.

Toxins (Basel). 2025-4-24

[2]
Toll-like receptor signaling in teleosts.

Sci China Life Sci. 2025-2-14

[3]
coordinates the IL-10 inducing activity of .

Microbiol Spectr. 2025-3-4

[4]
Lipoprotein Signal Peptide as Adjuvants: Leveraging Lipobox-Driven TLR2 Activation in Modern Vaccine Design.

Vaccines (Basel). 2025-1-2

[5]
Bacteria-activated macrophage membrane coated ROS-responsive nanoparticle for targeted delivery of antibiotics to infected wounds.

J Nanobiotechnology. 2024-12-19

[6]
Outer membrane lipoproteins: late to the party, but the center of attention.

J Bacteriol. 2025-1-31

[7]
Toll-like receptors as a missing link in Notch signaling cascade during neurodevelopment.

Front Mol Neurosci. 2024-11-27

[8]
The composition and function of membrane vesicles.

Microlife. 2021-4-12

[9]
Stimulation of Human Periodontal Ligament Fibroblasts Using Purified Dentilisin Extracted from .

Bio Protoc. 2022-12-20

[10]
Eating the Enemy: Mycoplasma Strategies to Evade Neutrophil Extracellular Traps (NETs) Promoting Bacterial Nucleotides Uptake and Inflammatory Damage.

Int J Mol Sci. 2022-11-30

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索