T 细胞记忆的多样性：丰富得令人尴尬。
Diversity in T cell memory: an embarrassment of riches.
机构信息
Department of Laboratory Medicine and Pathology and Center for Immunology, University of Minnesota, Minneapolis, MN 55455, USA.
出版信息
Immunity. 2009 Dec 18;31(6):859-71. doi: 10.1016/j.immuni.2009.11.007.
Abstract
The adaptive immune response meets the needs of the organism to generate effector cells capable of controlling pathogens but also leads to production of memory cells, which mediate more effective protection during rechallenge. In this review, we focus on the generation, maintenance, and function of memory T cells, with a special emphasis on the increasing evidence for great diversity among functional memory T cell subsets.
摘要
适应性免疫反应满足了机体生成能够控制病原体的效应细胞的需求，但也导致了记忆细胞的产生，这些细胞在再次遇到挑战时介导更有效的保护。在这篇综述中，我们专注于记忆 T 细胞的生成、维持和功能，特别强调了功能记忆 T 细胞亚群多样性的证据越来越多。
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