[Perinatal HIV-infection. Symptomatology, diagnosis and treatment].

Perinatally acquired HIV-infection is an increasing problem. Nine infants were born of HIV-infected mothers in Norway in 1988, and ten in 1989. Pediatric AIDS may involve a wide spectrum of clinical diseases with a high affinity to the central nervous system. The time from birth to development of clinical symptoms is relatively short. The overall mortality rate is extremely high in all age groups. Two children with perinatal HIV-infection are discussed in light of our treatment regimen. Children with immunosuppression and/or clinical symptoms are treated with zidovudine (azidotymidin/AZT) perorally. Children with repeated bacterial or opportunistic infections are also given immunoglobulin intravenously every 3rd to 4th week.