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[冰岛一家急症医院中老年人的收缩期杂音:患病率、二维和多普勒超声心动图的病因以及临床评估的敏感性和特异性。]

[Systolic murmurs of the elderly in an Icelandic acute care hospital: prevalence, etiology by 2D- and Doppler echocardiography and sensitivity and specificity of clinical assessment.].

作者信息

Egilsson T T, Jonasson T F, Gottskalksson G, Jonsson P V

出版信息

Laeknabladid. 1996 Sep;82(9):636-41.

Abstract

Acutely hospitalised elderly patients, from February 1993 to February 1994, excluding those with known valvular heart diseases, were examined by a resident. Those who had a systolic murmur were also auscultated by a cardiologist and a geriatrician and studied with 2D- and Doppler echocardiography. Of 213 potential study participants the resident auscultated 153 patients, 79-101 years old, with the mean age of 85+/-4 years, 61% of whom were women. Systolic murmurs were diagnosed in 80 of 153 patients or 53% of over the age of 80, 61% of women and 40% of men adjusted for sex (p<0,025). Fifty seven patients with systolic murmurs were evaluated with 2D- and Doppler echocardiography. Maximal Doppler gradients 3=30 mmHg, representing significant aortic stenosis were found in 8/57 subjects (14%), aortic sclerosis in 44 (77%), and mitral regurgitation in 25/57 (44%); 1 degrees on the scale of 1-4 in 19 of 25. The sensitivity and specificity of clinical examination for the detection of aortic stenosis was 62-100% and 71-77%, aortic sclerosis 54-56% and 85-92% and mitral regurgitation 24-52% and 69-97%, respectively. Systolic murmurs are prevalent in the aged and more so in women than men. 2D- and Doppler echocardiography is of value since the clinical diagnosis of aortic stenosis is difficult in light of the high prevalence of systolic murmurs most of which are due to aortic sclerosis or clinically nonsignificant mitral regurgitation. The results are comparable with other reported studies.

摘要

1993年2月至1994年2月期间,对急性住院的老年患者(不包括已知患有心脏瓣膜病的患者)进行了住院医师检查。对有收缩期杂音的患者,还由心脏病专家和老年病专家进行了听诊,并进行了二维和多普勒超声心动图检查。在213名潜在研究参与者中,住院医师听诊了153例患者,年龄在79至101岁之间,平均年龄为85±4岁,其中61%为女性。153例患者中有80例被诊断为收缩期杂音,即80岁以上患者的53%、经性别调整后女性的61%和男性的40%(p<0.025)。对57例有收缩期杂音的患者进行了二维和多普勒超声心动图评估。在57名受试者中有8名(14%)发现最大多普勒梯度≥30 mmHg,代表严重主动脉瓣狭窄;44名(77%)有主动脉硬化;25名(44%)有二尖瓣反流;25名中有19名在1-4级中为1级。临床检查检测主动脉瓣狭窄的敏感性和特异性分别为62%-100%和71%-77%,主动脉硬化为54%-56%和85%-92%,二尖瓣反流为24%-52%和69%-97%。收缩期杂音在老年人中很常见,女性比男性更常见。二维和多普勒超声心动图很有价值,因为鉴于收缩期杂音的高患病率,其中大多数是由于主动脉硬化或临床上无意义的二尖瓣反流,主动脉瓣狭窄的临床诊断很困难。这些结果与其他报道的研究结果相当。

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