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指甲剂量测定学:现状与展望。

Fingernail dosimetry: current status and perspectives.

机构信息

Naval Dosimetry Center, Bethesda, MD 20889, USA.

出版信息

Health Phys. 2010 Feb;98(2):296-300. doi: 10.1097/01.HP.0000347999.01948.74.

DOI:10.1097/01.HP.0000347999.01948.74
PMID:20065697
Abstract

A summary of recent developments in fingernail EPR dosimetry is presented in this paper. Until 2007, there had been a very limited number of studies of radiation-induced signals in fingernails. Although these studies showed some promising results, they were not complete with regard to the nature of non-radiation signals and the variability of dose dependence in fingernails. Recent study has shown that the two non-radiation components of the EPR spectrum of fingernails are originated from mechanical stress induced in the samples at their cut. The mechanical properties of fingernails were found to be very similar to those of a sponge; therefore, an effective way to eliminate their mechanical deformation is by soaking them in water. Stress caused by deformation can also significantly modify the dose response and radiation sensitivity. Consequently, it is critically important to take into account the mechanical stress in fingernail samples under EPR dose measurements. Obtained results have allowed formulating a prototype of a protocol for dose measurements in human fingernails.

摘要

本文综述了近年来指甲 EPR 剂量学的最新进展。截至 2007 年,仅有少数研究关注指甲中辐射诱导信号。尽管这些研究显示出一些有前途的结果,但它们在非辐射信号的本质和指甲剂量依赖性的可变性方面并不完整。最近的研究表明,指甲 EPR 光谱的两个非辐射分量源自在切割时样品中产生的机械应力。研究发现指甲的机械性能与海绵非常相似;因此,消除其机械变形的有效方法是将其浸泡在水中。由变形引起的应力也会显著改变剂量响应和辐射敏感性。因此,在 EPR 剂量测量中必须考虑指甲样品的机械应力。获得的结果允许制定用于人类指甲剂量测量的协议原型。

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