Torun Fuat, Mordeniz Cengiz, Baysal Zeynep, Avci Emel, Togrul Turhan, Karabag Hamza, Yildiz Ismail
Department of Neurosurgery, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
J Spinal Disord Tech. 2010 Feb;23(1):43-6. doi: 10.1097/BSD.0b013e318198793c.
Prospective, cohort, and clinical study.
It was proven that effective control of postoperative pain in lumbar disk surgery improves the patient's recovery. Despite the many advances in surgical and nonsurgical techniques, the most accurate approach in pain relief is still under debate.
In this study, our aim was to determine whether neural root blockade before the onset of noxious stimuli could inhibit the production of pain.
Forty-five patients undergoing unilateral 1 spinal level (lumbar 5) hemipartial laminectomy were included in the study. In 20 of the patients (group 2), 0.5 mL 2% lidocaine was infiltrated onto the neural root immediately after the exposure; the 25 patients in the control group (group 1) were not injected. All patients were monitored regarding pain determination using a visual analog scale, and the exact time of analgesic requirement during the first postoperative day was noted. Total analgesic dose given during the first postoperative day was also recorded.
Perineural lidocaine infiltration extended the early postoperative analgesic period. Although the pain was not completely suppressed, the lidocaine infiltration helped to manage the postoperative pain more effectively. The patients (group 2) who received lidocaine infiltration intraoperatively onto the neural root had a statistically significant longer time before analgesia requested (P<0.001) and also required significantly less analgesic when compared with the control group (P<0.001).
For preemptive analgesia for acute postoperative pain in laminectomy surgery, which remains a major concern, we suggest that lidocaine infiltration onto the dorsal neural sheath immediately before retraction of the root may extend the time before analgesia requested and the total analgesic drug consumption.
前瞻性队列临床研究。
已证实,有效控制腰椎间盘手术术后疼痛可促进患者康复。尽管手术和非手术技术取得了诸多进展,但缓解疼痛的最精确方法仍存在争议。
本研究旨在确定在有害刺激开始前进行神经根阻滞是否能抑制疼痛产生。
45例行单侧1个腰椎节段(腰5)半椎板切除术的患者纳入本研究。其中20例患者(2组),在神经根暴露后立即将0.5 mL 2%利多卡因注入神经根;对照组25例患者(1组)未注射。使用视觉模拟量表对所有患者的疼痛情况进行监测,并记录术后第一天需要镇痛的确切时间。同时记录术后第一天给予的总镇痛剂量。
神经周围利多卡因浸润延长了术后早期镇痛时间。尽管疼痛未被完全抑制,但利多卡因浸润有助于更有效地控制术后疼痛。术中接受神经根利多卡因浸润的患者(2组),与对照组相比,镇痛需求出现的时间在统计学上显著延长(P<0.001),且镇痛药物需求量也显著减少(P<0.001)。
对于椎板切除术急性术后疼痛的超前镇痛这一主要问题,我们建议在神经根牵开前立即将利多卡因浸润至背侧神经鞘,这可能会延长镇痛需求出现的时间以及减少总镇痛药物消耗量。