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桥小脑角表皮样囊肿伴三叉神经痛10年:一例报告

Cerebellopontine epidermoid presenting with trigeminal neuralgia for 10 years: a case report.

作者信息

Roka Yam B, Bista Prakash, Sharma Gopal R, Sultania Pawan K

机构信息

Neurological Surgery Unit, Department of Surgery, B.P.Koirala Institute of Health Sciences, Dharan, 7053, Nepal.

出版信息

Cases J. 2009 Dec 18;2:9345. doi: 10.1186/1757-1626-2-9345.

Abstract

Trigeminal neuralgia, also called tic douloureux, is a common and potentially disabling pain syndrome, which affects the trigeminal or fifth cranial nerve. The precise pathophysiology of Trigeminal neuralgia remains obscure. The disorder causes extreme, sporadic, sudden burning or shock-like face pain that lasts from few seconds to minutes and can be physically and mentally incapacitating. More than one nerve branch can be affected by the disorder. A 55-year-old female presented with pain over the left side of face for 10 years uncontrolled with carbamazepine. On examination the positive findings were reduced sensation by 25% over the left side of face with House and Brackman grade II facial nerve palsy. The corneal reflex was absent on left side. Magnetic resonance imaging showed left cerebellopontine angle (CPA) mass suggestive of an epidermoid involving the Vth nerve and Gasserian ganglion and extending into the middle cranial fossa. She underwent left suboccipital craniectomy and near total excision of the tumor with decompression of the V(th )nerve which was fully engulfed by the tumor. Postoperative the VII nerve palsy increased to grade III and she had 50% loss of sensation over left side. She had no further attacks of pain and hence tapered off the carbamazepine. TN caused by cerebellopontine angle epidermoids is uncommon and should be kept in view in all cases presenting with TN. The aim of surgery for epidermoids is to decompress the cranial nerves and brain stem and not total removal with its attendant morbidity and mortality.

摘要

三叉神经痛,也称为痛性抽搐,是一种常见且可能导致残疾的疼痛综合征,它会影响三叉神经或第五对脑神经。三叉神经痛的确切病理生理学仍不清楚。这种疾病会引起极端的、间歇性的、突然的灼烧样或电击样面部疼痛,持续数秒至数分钟,会使人身心失能。不止一个神经分支可能受到该疾病的影响。一名55岁女性因左侧面部疼痛10年,服用卡马西平无法控制前来就诊。检查发现,左侧面部感觉减退25%,伴有House-Brackman二级面神经麻痹。左侧角膜反射消失。磁共振成像显示左侧小脑脑桥角(CPA)肿块,提示表皮样囊肿累及第五脑神经和半月神经节,并延伸至中颅窝。她接受了左枕下颅骨切除术,几乎完全切除肿瘤并对被肿瘤完全包裹的第五脑神经进行减压。术后,面神经麻痹加重至三级,左侧感觉丧失50%。她没有再出现疼痛发作,因此逐渐停用了卡马西平。由小脑脑桥角表皮样囊肿引起的三叉神经痛并不常见,所有三叉神经痛病例都应考虑到这种情况。表皮样囊肿的手术目的是对脑神经和脑干进行减压,而不是进行可能带来发病率和死亡率的完全切除。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/99fc/2804725/c6b21dca3be5/1757-1626-2-9345-1.jpg

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