Son Dong Wuk, Choi Chang Hwa, Cha Seung Heon
Department of Neurosurgery, Medical Research Institute, School of Medicine, Pusan National University, Busan, Korea.
J Korean Neurosurg Soc. 2010 Apr;47(4):271-7. doi: 10.3340/jkns.2010.47.4.271. Epub 2010 Apr 30.
The purpose of this study is to evaluate the clinical characteristics and surgical outcome of cerebellopontine angle (CPA) epidermoids presenting with trigeminal neuralgia.
Between 1996 and 2004, 10 patients with typical symptoms of trigeminal neuralgia were found to have cerebellopontine angle epidermoids and treated surgically at our hospital. We retrospectively analyzed the clinico-radiological records of the patients.
Total resection was done in 6 patients (60%). Surgical removal of tumor and microvascular decompression of the trigeminal nerve were performed simultaneously in one case. One patient died due to postoperative aseptic meningitis. The others showed total relief from pain. During follow-up, no patients experienced recurrence of their trigeminal neuralgia (TN).
The clinical features of TN from CPA epidermoids are characterized by symptom onset at a younger age compared to TN from vascular causes. In addition to removal of the tumor, the possibility of vascular compression at the root entry zone of the trigeminal nerve should be kept in mind. If it exists, a microvascular decompression (MVD) should be performed. Recurrence of tumor is rare in both total and subtotal removal cases, but long-term follow-up is required.
本研究旨在评估以三叉神经痛为表现的桥小脑角(CPA)表皮样囊肿的临床特征及手术效果。
1996年至2004年间,我院发现10例有典型三叉神经痛症状的患者患有桥小脑角表皮样囊肿并接受了手术治疗。我们对这些患者的临床放射学记录进行了回顾性分析。
6例(60%)患者实现了全切。1例患者同时进行了肿瘤切除及三叉神经微血管减压术。1例患者因术后无菌性脑膜炎死亡。其他患者疼痛完全缓解。随访期间,无患者三叉神经痛(TN)复发。
与血管性病因导致的三叉神经痛相比,CPA表皮样囊肿所致三叉神经痛的临床特征为发病年龄较轻。除切除肿瘤外,应考虑三叉神经根入区血管压迫的可能性。若存在血管压迫,应行微血管减压术(MVD)。全切和次全切病例中肿瘤复发均少见,但仍需长期随访。