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Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling.
PLoS One. 2008;3(12):e4046. doi: 10.1371/journal.pone.0004046. Epub 2008 Dec 24.
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Activation of wingless targets requires bipartite recognition of DNA by TCF.
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APC is essential for targeting phosphorylated beta-catenin to the SCFbeta-TrCP ubiquitin ligase.
Mol Cell. 2008 Dec 5;32(5):652-61. doi: 10.1016/j.molcel.2008.10.023.
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Hum Mol Genet. 2009 Jan 15;18(2):213-26. doi: 10.1093/hmg/ddn338. Epub 2008 Oct 14.
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Trends Cell Biol. 2008 Dec;18(12):587-96. doi: 10.1016/j.tcb.2008.09.002. Epub 2008 Oct 9.
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A Wnt-fall for gene regulation: repression.
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