Bauer T W, Zehr R J, Belhobek G H, Marks K E
Department of Pathology, Cleveland Clinic Foundation, OH 44195.
Am J Surg Pathol. 1991 Apr;15(4):381-7. doi: 10.1097/00000478-199104000-00007.
Osteoid osteomas that arise at the end of a long bone, within the insertion of the joint capsule (juxta-articular, intra-articular), may cause misleading clinical, radiographic, and histologic findings, resulting in unnecessary diagnostic tests and a delay in definitive treatment. To clarify optimum diagnostic procedures, we reviewed 20 cases of juxta-articular osteoid osteomas and found a mean delay from presentation to correct diagnosis of 24 months. Plain radiographs were either negative or showed only secondary changes. A periosteal reaction and proliferative synovitis with chronic inflammation was common, which could be misinterpreted as rheumatoid arthritis. Optimum diagnostic procedures were a bone scan followed by plain tomograms and an excisional biopsy of the nidus.
发生于长骨末端、关节囊附着处(关节旁、关节内)的骨样骨瘤,可能会导致具有误导性的临床、影像学和组织学表现,从而引发不必要的诊断检查,并延误确定性治疗。为明确最佳诊断程序,我们回顾了20例关节旁骨样骨瘤病例,发现从出现症状到正确诊断的平均延迟时间为24个月。X线平片要么为阴性,要么仅显示继发性改变。骨膜反应和伴有慢性炎症的增生性滑膜炎很常见,这可能会被误诊为类风湿关节炎。最佳诊断程序是先进行骨扫描,然后行平片体层摄影,并对瘤巢进行切除活检。