Department of Pediatrics, Yuzuncu Yil University School of Medicine, Van, Turkey.
Hum Exp Toxicol. 2010 Mar;29(3):231-3. doi: 10.1177/0960327109359639. Epub 2010 Jan 12.
Scorpion stings represent an important and serious public health problem worldwide due to their high incidence and potentially severe and often fatal clinical manifestations. Children are at greater risk of developing severe cardiac, respiratory, and neurological complications due to lesser body surface area. Alpha receptor stimulation plays important role in the pathogenesis of pulmonary edema. Prazosin, a post synaptic alpha blocker, can be recommended as an effective drug in the treatment of serious scorpion envenomations with significant sympathetic symptoms. Oral prazosin is fast acting, easily available, relatively cheap, free from any anaphylaxis and highly effective.
蝎子蜇伤是一个重要且严重的全球公共卫生问题，这是由于其高发病率以及潜在的严重且常致命的临床表现。由于儿童的体表面积较小，因此他们面临更大的发生严重心脏、呼吸和神经并发症的风险。α受体刺激在肺水肿的发病机制中起重要作用。特拉唑嗪是一种突触后α阻滞剂，可作为具有明显交感神经症状的严重蝎子蜇伤的有效治疗药物。特拉唑嗪口服起效快、易于获得、相对便宜、无任何过敏反应且非常有效。
