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急性失代偿性心力衰竭:当代医学管理

Acute decompensated heart failure: contemporary medical management.

作者信息

Joseph Susan M, Cedars Ari M, Ewald Gregory A, Geltman Edward M, Mann Douglas L

机构信息

Division of Cardiology, Department of Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA.

出版信息

Tex Heart Inst J. 2009;36(6):510-20.

Abstract

Hospitalizations for acute decompensated heart failure are increasing in the United States. Moreover, the prevalence of heart failure is increasing consequent to an increased number of older individuals, as well as to improvement in therapies for coronary artery disease and sudden cardiac death that have enabled patients to live longer with cardiovascular disease. The main treatment goals in the hospitalized patient with heart failure are to restore euvolemia and to minimize adverse events. Common in-hospital treatments include intravenous diuretics, vasodilators, and inotropic agents. Novel pharmaceutical agents have shown promise in the treatment of acute decompensated heart failure and may simplify the treatment and reduce the morbidity associated with the disease. This review summarizes the contemporary management of patients with acute decompensated heart failure.

摘要

在美国,急性失代偿性心力衰竭的住院人数正在增加。此外,由于老年人口数量增加,以及冠状动脉疾病和心源性猝死治疗方法的改进使患者能够在患有心血管疾病的情况下活得更长,心力衰竭的患病率也在上升。心力衰竭住院患者的主要治疗目标是恢复血容量正常并尽量减少不良事件。常见的院内治疗包括静脉注射利尿剂、血管扩张剂和正性肌力药物。新型药剂在急性失代偿性心力衰竭的治疗中已显示出前景,可能会简化治疗并降低与该疾病相关的发病率。本综述总结了急性失代偿性心力衰竭患者的当代管理方法。

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