Rheumatology Department, Westmead Hospital, Sydney, NSW, Australia.
Clin Rheumatol. 2010 Apr;29(4):439-41. doi: 10.1007/s10067-009-1353-2.
This is the first reported case of pseudohypercalcaemia associated with type 2 cryoglobulinaemia, secondary to primary Sjögren's syndrome. Pseudohypercalcaemia is an asymptomatic syndrome and does not require specific treatment. However, cryoglobulins have been demonstrated to bind to calcium, affecting the cryoprecipitability, and consequently, altering the pathogenicity of the cryoglobulins. This first report highlights potential for further research into this intriguing phenomenon.
这是首例与 2 型冷球蛋白血症相关的假性高钙血症报告，其继发于原发性干燥综合征。假性高钙血症是一种无症状的综合征，不需要特殊治疗。然而，已证实冷球蛋白可与钙结合，影响冷沉淀，进而改变冷球蛋白的致病性。这首次报告突出了对这一有趣现象进行进一步研究的潜力。
