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一例原发性干燥综合征,合并冷球蛋白血症性肾小球肾炎、心包积液和胸腔积液。

A case of primary Sjögren's syndrome, complicated by cryoglobulinaemic glomerulonephritis, pericardial and pleural effusions.

作者信息

Suzuki H, Hickling P, Lyons C B

机构信息

Department of Rheumatology, Derriford Hospital, Plymouth, UK.

出版信息

Br J Rheumatol. 1996 Jan;35(1):72-5. doi: 10.1093/rheumatology/35.1.72.

Abstract

Primary Sjögren's syndrome (SS1) complicated by glomerulonephritis is rare and is usually associated with the presence of cryoglobulins. Cryoglobulinaemic glomerulonephritis as described in type II essential mixed cryoglobulinaemia, characterized by the presence of deposits of cryoglobgulins within the glomerular capillary lumen, occurring in SS1 has previously been reported only once in the literature. Our case was also complicated by pleural and pericardial effusions. We discuss the treatment options available for the renal lesion.

摘要

原发性干燥综合征(SS1)合并肾小球肾炎较为罕见,通常与冷球蛋白血症有关。II型原发性混合性冷球蛋白血症中所描述的冷球蛋白血症性肾小球肾炎,其特征为肾小球毛细血管腔内存在冷球蛋白沉积,在SS1中发生的情况此前在文献中仅报道过一次。我们的病例还合并有胸腔和心包积液。我们讨论了针对肾脏病变的可用治疗方案。

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