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[以色列流感的临床和病毒学监测——大流行性流感期间的实施情况]

[Clinical and virological surveillance of influenza in Israel--implementation during pandemic influenza].

作者信息

Bromberg Michal, Kaufman Zalman, Mandelboim Michal, Sefty Hanna, Shalev Varda, Marom Rachel, Mendelson Ella, Green Manfred S, Shohat Tamy

机构信息

Israel Center for Disease Control, Gertner Institute for Health Policy Research, Chaim Sheba Medical Center, Tel Hashomer, Israel.

出版信息

Harefuah. 2009 Sep;148(9):577-82, 659.

Abstract

BACKGROUND

Pandemic influenza surveillance has a central role in providing an updated situation for the health care system.

AIM

To describe the Israel Center for Disease Control (ICDC) pandemic influenza surveillance system.

METHODS

The ICDC conducts a seasonal influenza surveillance system based on patients' visits to community clinics (mainly Maccabi Healthcare Services) and emergency rooms for influenza-like illness (ILI) or pneumonia, and on laboratory confirmed nasopharyngeal swabs from ILI patients at designated sentinel clinics (tested at the Central Virology Laboratory). The laboratory based surveillance provides data on the active influenza strains, resistance to anti-viral drugs and match with the seasonal vaccine. The influenza surveillance network was strengthened since the level of the influenza pandemic alert was raised to phase 4 at the end of April 2009.

RESULTS

The first A/H1N1 2009 cases were identified by the surveillance system in the last week of May 2009. Local transmission was recorded in the second half of June 2009. At this time there was an increase in the rates of patient visits to outpatient clinics for ILI, especially in the age group 0-18 years old and in residents of Tel Aviv, Central and Jerusalem districts. By the end of July 2009 there was an increase in pneumonia cases (mainly 2-18 years old) in community clinics.

CONCLUSIONS

Once the pandemic influenza began spreading, the ICDC surveillance system provided a valid picture which facilitated the decision to stop laboratory confirmation of each community case and rely on the ICDC surveillance system as the main source for information.

摘要

背景

大流行性流感监测在为卫生保健系统提供最新情况方面发挥着核心作用。

目的

描述以色列疾病控制中心(ICDC)的大流行性流感监测系统。

方法

ICDC开展季节性流感监测系统,该系统基于患者因流感样疾病(ILI)或肺炎前往社区诊所(主要是Maccabi医疗服务机构)和急诊室就诊的情况,以及指定哨点诊所ILI患者经实验室确诊的鼻咽拭子(在中央病毒学实验室检测)。基于实验室的监测提供有关现行流感毒株、对抗病毒药物的耐药性以及与季节性疫苗匹配情况的数据。自2009年4月底流感大流行警戒级别升至4级以来,流感监测网络得到了加强。

结果

2009年5月的最后一周,监测系统发现了首例2009年甲型H1N1流感病例。2009年6月下旬记录到本地传播。此时,门诊诊所因ILI就诊的患者比例有所增加,尤其是在0 - 18岁年龄组以及特拉维夫、中部和耶路撒冷地区的居民中。到2009年7月底,社区诊所的肺炎病例(主要是2 - 18岁)有所增加。

结论

一旦大流行性流感开始传播,ICDC监测系统提供了有效的情况,这有助于做出停止对每例社区病例进行实验室确诊并将ICDC监测系统作为主要信息来源的决定。

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