南非分离的新型沙粒病毒——美利奴游走病毒的基因组和系统进化特征分析。
Genomic and phylogenetic characterization of Merino Walk virus, a novel arenavirus isolated in South Africa.
机构信息
Center for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
出版信息
J Gen Virol. 2010 May;91(Pt 5):1315-24. doi: 10.1099/vir.0.017798-0. Epub 2010 Jan 13.
Abstract
Merino Walk virus (MWV), a proposed novel tentative species of the family Arenaviridae, was isolated from a rodent, Myotomys unisulcatus, collected at Merino Walk, Eastern Cape, South Africa, in 1985. Full-length genomic sequence confirmed MWV as an arenavirus related distantly to Mobala, Mopeia and Ippy viruses, all members of the Old World arenavirus complex. We propose MWV as a tentative novel species in the Lassa-lymphocytic choriomeningitis virus complex, based on its isolation from a novel rodent species and its genetic and serological characteristics.
摘要
美利奴走病毒（MWV）是一种新型的沙粒病毒科暂定种，于 1985 年从南非东开普省美利奴步道采集的一种啮齿动物 Myotomys unisulcatus 中分离得到。全长基因组序列证实 MWV 是一种与莫博拉病毒、莫佩亚病毒和伊皮病毒密切相关的沙粒病毒，它们都是旧世界沙粒病毒复合物的成员。鉴于该病毒是从一种新型啮齿动物中分离出来的，且具有遗传和血清学特征，我们将其提议为拉沙-淋巴细胞性脉络丛脑膜炎病毒复合物中的一种新型暂定种。
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