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设计与初步性能的 PlanTIS:一个高分辨率正电子发射断层成像仪的植物。

Design and initial performance of PlanTIS: a high-resolution positron emission tomograph for plants.

机构信息

Central Institute for Electronics, Forschungszentrum Juelich, D-52425 Juelich, Germany.

出版信息

Phys Med Biol. 2010 Feb 7;55(3):635-46. doi: 10.1088/0031-9155/55/3/006. Epub 2010 Jan 13.

Abstract

Positron emitters such as (11)C, (13)N and (18)F and their labelled compounds are widely used in clinical diagnosis and animal studies, but can also be used to study metabolic and physiological functions in plants dynamically and in vivo. A very particular tracer molecule is (11)CO(2) since it can be applied to a leaf as a gas. We have developed a Plant Tomographic Imaging System (PlanTIS), a high-resolution PET scanner for plant studies. Detectors, front-end electronics and data acquisition architecture of the scanner are based on the ClearPET system. The detectors consist of LSO and LuYAP crystals in phoswich configuration which are coupled to position-sensitive photomultiplier tubes. Signals are continuously sampled by free running ADCs, and data are stored in a list mode format. The detectors are arranged in a horizontal plane to allow the plants to be measured in the natural upright position. Two groups of four detector modules stand face-to-face and rotate around the field-of-view. This special system geometry requires dedicated image reconstruction and normalization procedures. We present the initial performance of the detector system and first phantom and plant measurements.

摘要

正电子发射体,如 (11)C、(13)N 和 (18)F 及其标记化合物被广泛用于临床诊断和动物研究,也可用于动态和体内研究植物的代谢和生理功能。(11)CO(2)是一种非常特殊的示踪剂分子,因为它可以作为气体应用于叶片。我们开发了一种植物断层成像系统(PlanTIS),这是一种用于植物研究的高分辨率 PET 扫描仪。扫描仪的探测器、前端电子学和数据采集架构基于 ClearPET 系统。探测器由 LSO 和 LuYAP 晶体组成,采用磷光体配置,与位置灵敏光电倍增管耦合。信号由自由运行的 ADC 连续采样,并以列表模式格式存储数据。探测器被布置在一个水平面上,以便可以让植物在自然直立位置进行测量。两组四个探测器模块面对面排列,并围绕视场旋转。这种特殊的系统几何形状需要专用的图像重建和归一化程序。我们展示了探测器系统的初步性能以及首次进行的体模和植物测量结果。

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