Hirachand S, Lakhey M, Akhter J, Thapa B
Department of Pathology, Kathmandu Medical College, Sinamangal, Nepal.
Kathmandu Univ Med J (KUMJ). 2009 Apr-Jun;7(26):139-42. doi: 10.3126/kumj.v7i2.2707.
Fine Needle Aspiration Cytology (FNAC) is a simple and rapid diagnostic technique. Because of early availability of results, simplicity, minimal trauma and complications, the aspiration cytology is now considered a valuable diagnostic aid and is part and parcel of a pathologist's repertoire.
The aim of the study was to evaluate the results of fine needle aspiration cytology (FNAC) of lymph nodes in our institution in comparison to result of histopathology.
The present study on 130 patients of lymphadenopathy was conducted in the Department of Pathology Kathmandu Medical College Teaching hospital, Kathmandu from June 2006 to May 2008 (2 years).
In this series of FNAC cervical lymph nodes were 66 (50.76%), and axillary lymph nodes were 20 (15.38%). Male to female ratio of the patients was 1: 0.9. The age of patients ranged from 3 to 85 years. FNAC diagnosis was found to be as follows : reactive hyperplasia 54( 41.55%), tubercular lymphadenitis 36 (28 %), metastatic carcinoma 16 (12.3%), granulomatous lymphadenitis 12 ( 9.2 % ), lymphoma 8 (6%) and suppurative lymphadenitis 4(3%) . Out of 28 cases of FNAC 26 (92.85%) were consistent with histopathological diagnosis of tubercular lymphadenitis. In metastatic carcinoma to lymph nodes sensitivity and specificity of FNAC were 100% each.
FNAC is useful and reliable in diagnosing neoplastic and non- neoplastic lesions of lymph nodes. It helps in planning surgery for malignant cases, where definitive operative intervention can be performed in one session.
细针穿刺抽吸细胞学检查(FNAC)是一种简单快速的诊断技术。由于结果获取早、操作简单、创伤小且并发症少,抽吸细胞学检查现在被认为是一种有价值的诊断辅助手段,是病理学家全部技能的重要组成部分。
本研究旨在评估我院淋巴结细针穿刺抽吸细胞学检查(FNAC)的结果,并与组织病理学结果进行比较。
本研究于2006年6月至2008年5月(2年)在加德满都医学院教学医院病理科对130例淋巴结病患者进行。
在这一系列FNAC检查中,颈部淋巴结66例(50.76%),腋窝淋巴结20例(15.38%)。患者男女比例为1:0.9。患者年龄范围为3至85岁。FNAC诊断结果如下:反应性增生54例(41.55%),结核性淋巴结炎36例(28%),转移性癌16例(12.3%),肉芽肿性淋巴结炎12例(9.2%),淋巴瘤8例(6%),化脓性淋巴结炎4例(3%)。在28例FNAC诊断为结核性淋巴结炎的病例中,26例(92.85%)与组织病理学诊断一致。在转移性癌至淋巴结的诊断中,FNAC的敏感性和特异性均为100%。
FNAC在诊断淋巴结的肿瘤性和非肿瘤性病变方面是有用且可靠的。它有助于为恶性病例制定手术计划,在这种情况下可以一次进行确定性手术干预。