Gray Matthew J, Biyani Ashok, Smith Asher
Department of Orthopaedic Surgery, The University of Toledo College of Medicine, Toledo, OH 43614, USA.
J Spinal Disord Tech. 2010 May;23(3):157-61. doi: 10.1097/BSD.0b013e31819e31a4.
STUDY DESIGN/SETTING: Retrospective review of clinical outcomes after anterior cervical discectomy and fusion (ACDF) surgery with allograft and plating in patients over 55 years of age.
To evaluate the results of ACDF surgery in patients aged 55 years and older.
ACDF surgery has been a standard treatment for cervical degenerative and herniated disc disease for many years. Previous assessments of efficacy have used patient perceived outcome measures including the Neck Disability Index (NDI) and the Short Form 36 Question Health Questionnaire (SF-36). Patient perceived outcome after ACDF surgery in an age-specific cohort (55 y and older) has not been documented previously.
Fifty-two consecutive patients over 55 years of age who underwent 1 to 3 level ACDF with allograft and plating were identified. Patient perceived outcome questionnaires (NDI and SF-36) were available for 44 patients. There were 28 females and 16 males. Mean age at time of surgery was 61.8 years. Average length of follow-up was 25.2 months (12 to 54 mo).
All but one patient demonstrated radiographic healing of the fusion site at the time of their last follow-up. The mean improvement of these 10 groups (total NDI score) was statistically significant (difference =-9.47, t=5.6390, P=1.5198E-06). There was a statistically significant decrease in disability in 7 of the 8 SF-36 categories as well. The mean of the 8 SF-36 categories (total SF-36) improved significantly (improvement=11.92, t=-3.6857, P=0.0007).
On the basis of our statistically significant improvement in NDI and SF-36 scores, as a measure of patient perceived outcome after ACDF surgery, outcomes after ACDF surgery in patients over 55 years of age are not significantly different than those of a younger patient population.
研究设计/背景:对55岁以上接受同种异体骨移植和钢板固定的前路颈椎间盘切除融合术(ACDF)后的临床结果进行回顾性分析。
评估55岁及以上患者ACDF手术的效果。
多年来,ACDF手术一直是治疗颈椎退行性病变和椎间盘突出症的标准方法。以往对疗效的评估采用患者自我感知的结果指标,包括颈部功能障碍指数(NDI)和简短健康调查问卷36项(SF-36)。此前尚未有关于特定年龄组(55岁及以上)ACDF手术后患者自我感知结果的记录。
确定52例连续接受1至3节段ACDF同种异体骨移植和钢板固定的55岁以上患者。44例患者有患者自我感知结果调查问卷(NDI和SF-36)。其中女性28例,男性16例。手术时的平均年龄为61.8岁。平均随访时间为25.2个月(12至54个月)。
除1例患者外,所有患者在最后一次随访时融合部位均显示影像学愈合。这10组(NDI总分)的平均改善具有统计学意义(差异=-9.47,t=5.6390,P=1.5198E-06)。SF-36的8个类别中有7个类别的残疾程度也有统计学意义的下降。8个SF-36类别(SF-36总分)的平均值有显著改善(改善值=11.92,t=-3.6857,P=0.0007)。
基于我们在NDI和SF-36评分上具有统计学意义的改善,作为ACDF手术后患者自我感知结果的衡量指标,55岁以上患者ACDF手术后的结果与年轻患者群体的结果没有显著差异。