• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

对55岁及以上接受颈椎前路椎间盘切除融合术患者的患者自我感知结局的回顾性分析。

A retrospective analysis of patient perceived outcomes in patients 55 years and older undergoing anterior cervical discectomy and fusion.

作者信息

Gray Matthew J, Biyani Ashok, Smith Asher

机构信息

Department of Orthopaedic Surgery, The University of Toledo College of Medicine, Toledo, OH 43614, USA.

出版信息

J Spinal Disord Tech. 2010 May;23(3):157-61. doi: 10.1097/BSD.0b013e31819e31a4.

DOI:10.1097/BSD.0b013e31819e31a4
PMID:20072034
Abstract

STUDY DESIGN/SETTING: Retrospective review of clinical outcomes after anterior cervical discectomy and fusion (ACDF) surgery with allograft and plating in patients over 55 years of age.

OBJECTIVE

To evaluate the results of ACDF surgery in patients aged 55 years and older.

SUMMARY OF BACKGROUND DATA

ACDF surgery has been a standard treatment for cervical degenerative and herniated disc disease for many years. Previous assessments of efficacy have used patient perceived outcome measures including the Neck Disability Index (NDI) and the Short Form 36 Question Health Questionnaire (SF-36). Patient perceived outcome after ACDF surgery in an age-specific cohort (55 y and older) has not been documented previously.

METHODS

Fifty-two consecutive patients over 55 years of age who underwent 1 to 3 level ACDF with allograft and plating were identified. Patient perceived outcome questionnaires (NDI and SF-36) were available for 44 patients. There were 28 females and 16 males. Mean age at time of surgery was 61.8 years. Average length of follow-up was 25.2 months (12 to 54 mo).

RESULTS

All but one patient demonstrated radiographic healing of the fusion site at the time of their last follow-up. The mean improvement of these 10 groups (total NDI score) was statistically significant (difference =-9.47, t=5.6390, P=1.5198E-06). There was a statistically significant decrease in disability in 7 of the 8 SF-36 categories as well. The mean of the 8 SF-36 categories (total SF-36) improved significantly (improvement=11.92, t=-3.6857, P=0.0007).

CONCLUSIONS

On the basis of our statistically significant improvement in NDI and SF-36 scores, as a measure of patient perceived outcome after ACDF surgery, outcomes after ACDF surgery in patients over 55 years of age are not significantly different than those of a younger patient population.

摘要

研究设计/背景:对55岁以上接受同种异体骨移植和钢板固定的前路颈椎间盘切除融合术(ACDF)后的临床结果进行回顾性分析。

目的

评估55岁及以上患者ACDF手术的效果。

背景资料总结

多年来,ACDF手术一直是治疗颈椎退行性病变和椎间盘突出症的标准方法。以往对疗效的评估采用患者自我感知的结果指标,包括颈部功能障碍指数(NDI)和简短健康调查问卷36项(SF-36)。此前尚未有关于特定年龄组(55岁及以上)ACDF手术后患者自我感知结果的记录。

方法

确定52例连续接受1至3节段ACDF同种异体骨移植和钢板固定的55岁以上患者。44例患者有患者自我感知结果调查问卷(NDI和SF-36)。其中女性28例,男性16例。手术时的平均年龄为61.8岁。平均随访时间为25.2个月(12至54个月)。

结果

除1例患者外,所有患者在最后一次随访时融合部位均显示影像学愈合。这10组(NDI总分)的平均改善具有统计学意义(差异=-9.47,t=5.6390,P=1.5198E-06)。SF-36的8个类别中有7个类别的残疾程度也有统计学意义的下降。8个SF-36类别(SF-36总分)的平均值有显著改善(改善值=11.92,t=-3.6857,P=0.0007)。

结论

基于我们在NDI和SF-36评分上具有统计学意义的改善,作为ACDF手术后患者自我感知结果的衡量指标,55岁以上患者ACDF手术后的结果与年轻患者群体的结果没有显著差异。

相似文献

1
A retrospective analysis of patient perceived outcomes in patients 55 years and older undergoing anterior cervical discectomy and fusion.对55岁及以上接受颈椎前路椎间盘切除融合术患者的患者自我感知结局的回顾性分析。
J Spinal Disord Tech. 2010 May;23(3):157-61. doi: 10.1097/BSD.0b013e31819e31a4.
2
Results of the prospective, randomized, controlled multicenter Food and Drug Administration investigational device exemption study of the ProDisc-C total disc replacement versus anterior discectomy and fusion for the treatment of 1-level symptomatic cervical disc disease.关于ProDisc-C全椎间盘置换术与前路椎间盘切除融合术治疗单节段有症状颈椎间盘疾病的前瞻性、随机、对照、多中心食品药品监督管理局研究性器械豁免研究结果。
Spine J. 2009 Apr;9(4):275-86. doi: 10.1016/j.spinee.2008.05.006. Epub 2008 Sep 6.
3
Artificial disc versus fusion: a prospective, randomized study with 2-year follow-up on 99 patients.人工椎间盘与融合术:一项对99例患者进行2年随访的前瞻性随机研究。
Spine (Phila Pa 1976). 2007 Dec 15;32(26):2933-40; discussion 2941-2. doi: 10.1097/BRS.0b013e31815d0034.
4
Clinical outcomes of Bryan cervical disc arthroplasty a prospective, randomized, controlled, single site trial with 48-month follow-up.Bryan颈椎间盘置换术的临床结果:一项前瞻性、随机、对照、单中心试验,随访48个月。
J Spinal Disord Tech. 2010 Aug;23(6):367-71. doi: 10.1097/BSD.0b013e3181bb8568.
5
Does rigid instrumentation increase the fusion rate in one-level anterior cervical discectomy and fusion?在单节段颈椎前路椎间盘切除融合术中,使用坚强内固定是否会提高融合率?
Spine J. 2004 Nov-Dec;4(6):636-43. doi: 10.1016/j.spinee.2004.04.010.
6
Effect on clinical outcomes of patient pain expectancies and preoperative Mental Component Summary scores from the 36-Item Short Form Health Survey following anterior cervical discectomy and fusion.颈椎前路椎间盘切除融合术后患者疼痛预期和 36 项简明健康调查心理成分综合评分对临床结局的影响。
J Neurosurg Spine. 2011 Nov;15(5):486-90. doi: 10.3171/2011.6.SPINE11114. Epub 2011 Aug 5.
7
ProDisc-C and anterior cervical discectomy and fusion as surgical treatment for single-level cervical symptomatic degenerative disc disease: five-year results of a Food and Drug Administration study.ProDisc-C 与前路颈椎间盘切除融合术治疗单节段症状性颈椎退行性椎间盘疾病:一项食品和药物管理局研究的 5 年结果。
Spine (Phila Pa 1976). 2013 Feb 1;38(3):203-9. doi: 10.1097/BRS.0b013e318278eb38.
8
Anterior decompression and interbody fusion with BAK/C for cervical disc degenerative disorders.采用BAK/C前路减压及椎间融合术治疗颈椎间盘退变疾病。
J Spinal Disord Tech. 2009 Jun;22(4):240-5. doi: 10.1097/BSD.0b013e31816d5f7e.
9
Randomized, prospective, and controlled clinical trial of pulsed electromagnetic field stimulation for cervical fusion.脉冲电磁场刺激用于颈椎融合的随机、前瞻性对照临床试验。
Spine J. 2008 May-Jun;8(3):436-42. doi: 10.1016/j.spinee.2007.06.006. Epub 2007 Jul 17.
10
MOS short form 36 and Oswestry Disability Index outcomes in lumbar fusion: a multicenter experience.腰椎融合术的MOS简表36和奥斯威斯利功能障碍指数结果:一项多中心经验
Spine J. 2006 Jan-Feb;6(1):21-6. doi: 10.1016/j.spinee.2005.09.004.

引用本文的文献

1
Quality of Life in Patients Undergoing Spine Surgery: Systematic Review and Meta-Analysis.接受脊柱手术患者的生活质量:系统评价与荟萃分析。
Global Spine J. 2019 Feb;9(1):67-76. doi: 10.1177/2192568217701104. Epub 2018 Jul 29.
2
Impact of old age on patient-report outcomes and cost utility for anterior cervical discectomy and fusion surgery for degenerative spine disease.老年对退行性脊柱疾病前路颈椎间盘切除融合术患者报告结局及成本效用的影响。
Eur Spine J. 2017 Apr;26(4):1236-1245. doi: 10.1007/s00586-016-4835-3. Epub 2016 Nov 24.
3
Clinical outcome of anterior vs posterior approach for cervical spondylotic myelopathy.
脊髓型颈椎病前路与后路手术的临床疗效
J Orthop. 2016 Mar 26;13(3):123-6. doi: 10.1016/j.jor.2016.03.006. eCollection 2016 Sep.
4
Postoperative cervical haematoma complicated by ipsilateral carotid thrombosis and aphasia after anterior cervical fusion: a case report.颈椎前路融合术后并发同侧颈动脉血栓形成和失语的颈部血肿:一例报告
Case Rep Med. 2013;2013:590639. doi: 10.1155/2013/590639. Epub 2013 Mar 7.