Van Hook J W
Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston.
Crit Care Clin. 1991 Jan;7(1):215-23.
Hypermagnesemia is an often-overlooked problem in acute medical care situations. Magnesium is used in several areas of medicine and for various reasons. It also is found in many seemingly innocuous cathartics and gastrointestinal medications. Magnesium replacement in enteral or parenteral feeding and magnesium deficiency is addressed often. Despite the necessity to consider magnesium in several situations, many physicians are relatively unfamiliar with the use of magnesium in their patients. Magnesium is often used in patients with renal insufficiency, which further increases the risk of hypermagnesemia. Fortunately, the evaluation and treatment of hypermagnesemia is relatively straightforward. Calcium reversal of life-threatening sequelae, diuresis or dialysis to augment elimination of magnesium, and supportive care until the acute manifestations of the disorder resolve are the mainstays of therapy for hypermagnesemia. Recognition of patients at risk for the disorder and careful consideration of magnesium therapy will allow for prevention or early diagnosis of the disorder.
高镁血症在急性医疗护理情况下常常是一个被忽视的问题。镁在医学的多个领域有应用,且原因各异。它还存在于许多看似无害的泻药和胃肠道药物中。肠内或肠外营养中的镁补充以及镁缺乏的问题常被提及。尽管在多种情况下有必要考虑镁的问题,但许多医生对在患者中使用镁相对不熟悉。镁常用于肾功能不全的患者,这进一步增加了高镁血症的风险。幸运的是,高镁血症的评估和治疗相对简单直接。用钙逆转危及生命的后遗症、利尿或透析以增加镁的排出,以及在该病症的急性表现消退之前进行支持性护理,是高镁血症治疗的主要方法。识别有患该病症风险的患者并仔细考虑镁治疗,将有助于预防或早期诊断该病症。