Horino Taro, Ichii Osamu, Terada Yoshio
Department of Endocrinology, Metabolism, and Nephrology, Kochi Medical School, Japan.
Laboratory of Anatomy, Department of Biomedical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Japan.
Intern Med. 2019 Apr 15;58(8):1123-1126. doi: 10.2169/internalmedicine.1927-18. Epub 2018 Dec 18.
A 79-year-old Japanese woman presented with consciousness disturbance, hypercalcemia, and hypermagnesemia. She had rheumatoid arthritis and osteoporosis. Three months before admission, she was treated with oral calcitriol for osteoporosis. Two months before admission, she was treated with magnesium oxide for constipation. One month before admission, she underwent articular femoral bone replacement. Two weeks postoperatively, consciousness disturbance and elevated serum calcium levels were observed, and she was transferred to our hospital. On admission, her laboratory data showed elevated serum magnesium and creatinine levels. This is a rare case of coexistent hypercalcemia and hypermagnesemia associated with consciousness disturbance and acute kidney injury.
一名79岁的日本女性出现意识障碍、高钙血症和高镁血症。她患有类风湿性关节炎和骨质疏松症。入院前三个月，她因骨质疏松症接受骨化三醇口服治疗。入院前两个月，她因便秘接受氧化镁治疗。入院前一个月，她接受了股骨关节置换术。术后两周，观察到意识障碍和血清钙水平升高，随后她被转至我院。入院时，她的实验室检查数据显示血清镁和肌酐水平升高。这是一例罕见的同时伴有意识障碍和急性肾损伤的高钙血症和高镁血症病例。
