猪地西泮结合抑制因子（DBI）在大鼠内分泌胰腺中的免疫组织化学定位。
Immunohistochemical localization of porcine diazepam-binding inhibitor (DBI) to rat endocrine pancreas.
作者信息
Johansson O, Hilliges M, Ostenson C G, Sandberg E, Efendic S, Mutt V
机构信息
Department of Histology and Neurobiology, Karolinska Institutet, Stockholm, Sweden.
出版信息
Cell Tissue Res. 1991 Feb;263(2):395-8. doi: 10.1007/BF00318781.
The occurrence of diazepam-binding inhibitor (DBI), isolated and characterized from porcine upper intestine, was examined in the pancreas of Sprague-Dawley albino rats using indirect immunofluorescence. The polypeptide was found in the endocrine Langerhans islets and, utilizing double-labelling controls, it was shown to be present within the peripherally located glucagon-containing cells. Regulation of islet hormone production may therefore be under DBI control.
利用间接免疫荧光法，对从猪的上段肠道分离并鉴定出的地西泮结合抑制剂（DBI）在斯普拉格-道利白化大鼠胰腺中的出现情况进行了检测。在胰岛内分泌细胞中发现了这种多肽，通过双标记对照显示，它存在于周边含胰高血糖素的细胞内。因此，胰岛激素的产生调控可能受DBI控制。
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