1例羊膜移植治疗诺卡菌性角膜炎不愈病例

Rahimi Firoozeh, Aghsaie Fard Masood, Soltani Mogaddam Reza

J Ocul Biol Dis Infor. 2009 Mar 10;2(1):37-9. doi: 10.1007/s12177-009-9019-5.

A patient with severe non-healing microscopically proven Nocardia keratitis was treated with maximal topical amikacin followed by amniotic membrane transplantation (AMT) 2 months later (single-layer epithelial side-down). Epithelial healing was achieved, but neovascularization continued. This case report indicates that AMT combined with topical antibiotic provides pain relief and allows epithelial healing in severe Nocardia keratitis.

一名经显微镜检查确诊为严重不愈合的诺卡菌性角膜炎患者，先接受了最大剂量的局部阿米卡星治疗，2个月后进行了羊膜移植（AMT，单层上皮面朝下）。上皮愈合得以实现，但新生血管化仍在继续。本病例报告表明，AMT联合局部抗生素可缓解严重诺卡菌性角膜炎的疼痛并促进上皮愈合。