Soleimani Mohammad, Masoumi Ahmad, Khodavaisy Sadegh, Heidari Mostafa, Haydar Ali A, Izadi Alireza
Ocular Trauma and Emergency Department, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
J Ophthalmic Inflamm Infect. 2020 Dec 2;10(1):36. doi: 10.1186/s12348-020-00228-w.
Nocardia species are an uncommon but important cause of keratitis. The purpose of this review is to discus previous published papers relation to the epidemiology, etiology, diagnosis and management of Nocardia keratitis. Nocardia asteroides is the most frequently reported from Nocardia keratitis. Pain, photophobia, blepharospasm and lid swelling are mainly clinical manifestations. Usual risk factors for Nocardia keratitis are trauma, surgery, corticosteroids, and contact lens wear. Several antibiotics were used for treatment of Nocardia infection but according to studies, topical amikacin is the drug of choice for Nocardia keratitis. Topical steroid should not prescribe in these patients. In conclusion, although Nocardia keratitis is rare, early diagnosis and treatment are essential to prevent any scar formation and preserve a good visual acuity.
诺卡菌属是一种引起角膜炎的罕见但重要的病因。本综述的目的是探讨先前发表的与诺卡菌性角膜炎的流行病学、病因、诊断和治疗相关的论文。星形诺卡菌是诺卡菌性角膜炎最常报道的病原菌。疼痛、畏光、眼睑痉挛和眼睑肿胀是主要临床表现。诺卡菌性角膜炎常见的危险因素是外伤、手术、使用皮质类固醇和佩戴隐形眼镜。几种抗生素被用于治疗诺卡菌感染,但根据研究,局部使用阿米卡星是诺卡菌性角膜炎的首选药物。这些患者不应开具局部类固醇药物。总之,虽然诺卡菌性角膜炎很少见,但早期诊断和治疗对于预防任何瘢痕形成和保持良好视力至关重要。