McGue Matt
Department of Psychology, University of Minnesota.
Xin Li Xue Bao. 2008 Jan 1;40(10):1073-1087. doi: 10.3724/sp.j.1041.2008.01073.
Although genetic models were in the ascendance within psychology during the early 20(th) century, the association of early behavioral genetic research with the eugenics movement served to discredit the field in the eyes of many. Twin and adoption studies throughout the latter half of the 20(th) century helped to reestablish the importance of behavioral genetic models and set the stage for the current focus of the field on developing and testing models of gene-environment interplay. Research findings on developmental behavioral genetic research, gene-environment interaction, and the use of behavioral genetic models to test causal hypotheses are used to highlight the contributions of contemporary behavioral genetic research to psychological research. It is argued that future efforts to investigate models of gene-environment interplay will depend heavily of the field's ability to identify the specific genetic variants that contribute to individual differences in behavior. The anticipated yield from genome-wide association studies gives much reason to be optimistic about the future vitality of behavior genetics.
尽管在20世纪早期遗传模型在心理学领域逐渐占据主导地位，但早期行为遗传学研究与优生学运动的关联，在许多人眼中有损该领域的声誉。贯穿20世纪后半叶的双胞胎和收养研究，有助于重新确立行为遗传模型的重要性，并为该领域当前专注于开发和测试基因-环境相互作用模型奠定了基础。关于发展行为遗传学研究、基因-环境相互作用以及使用行为遗传模型来检验因果假设的研究结果，被用来凸显当代行为遗传学研究对心理学研究的贡献。有人认为，未来对基因-环境相互作用模型的研究工作，将在很大程度上取决于该领域识别出导致个体行为差异的特定基因变异的能力。全基因组关联研究的预期成果，让人们有充分理由对行为遗传学的未来活力持乐观态度。
