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儿童急性淋巴细胞白血病诱导化疗期间发生原发性皮肤毛霉菌病。

'Primary cutaneous mucormycosis during induction chemotherapy in a child with acute lymphoblastic leukemia'.

机构信息

Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Indian J Pediatr. 2009 Nov;76(11):1161-3. doi: 10.1007/s12098-009-0280-1. Epub 2010 Jan 14.

Abstract

We report a child with acute lymphoblastic leukemia who developed primary cutaneous mucormycosis at the site of lumbar puncture during induction chemotherapy. Though high mortality rates are reported with invasive mucormycosis, prompt biopsy, early identification and antifungal therapy using a combination regime of amphotericin-B and rifampicin along with extensive surgical debridement led to complete cure of the lesions in the index case.

摘要

我们报告了一例在诱导化疗期间腰椎穿刺部位发生急性淋巴细胞白血病的患儿原发性皮肤毛霉菌病。尽管侵袭性毛霉菌病的死亡率很高,但及时活检、早期识别和使用两性霉素 B 和利福平联合治疗方案以及广泛的手术清创术可彻底治愈该病例的病变。

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