Linder N, Keller N, Huri C, Kuint J, Goldshmidt-Reuven A, Barzilai A
Department of Neonatology, The Chaim Sheba Medical Center, Tel-Hashomer, Israel.
Am J Perinatol. 1998 Jan;15(1):35-8. doi: 10.1055/s-2007-993895.
Mucormycosis is an uncommon infection caused by fungi of the order Mucorales, family Mucoraceae, and almost always occurs in individuals with predisposing factors such as diabetes mellitus, metabolic acidosis, or immunodeficiency states. Although mucormycosis is a rare infection in childhood, sporadic cases of skin infections have been described in young infants and older children; primary skin infection has been associated with multiple nosocomial outbreaks caused by contaminated elastic bandages. In all reported cases involving premature infants, the elimination of the infection involved surgical debridement. We report for the first time successful conservative treatment with intravenous amphotericin B in a premature infant with primary cutaneous infection caused by Rhizopus oryzae.
毛霉病是一种由毛霉目、毛霉科真菌引起的罕见感染，几乎总是发生在有易感因素的个体中，如糖尿病、代谢性酸中毒或免疫缺陷状态。虽然毛霉病在儿童期是一种罕见感染，但已报道了婴幼儿和大龄儿童的散发性皮肤感染病例；原发性皮肤感染与由受污染的弹力绷带引起的多起医院感染暴发有关。在所有报告的涉及早产儿的病例中，感染的消除都涉及手术清创。我们首次报告了用静脉注射两性霉素B成功保守治疗一名由米根霉引起原发性皮肤感染的早产儿。
