Richards W, Roth R M, Church J A
Childrens Hospital of Los Angeles, Division of Allergy and Clinical Immunology, California 90054.
Clin Pediatr (Phila). 1991 Feb;30(2):88-92. doi: 10.1177/000992289103000205.
A review of outpatients diagnosed with sinusitis during the previous year by the allergy services of Childrens Hospital of Los Angeles and Kaiser Permanente, Orange County, revealed 34 patients who had protracted discomforting and debilitating symptoms. The mean duration of symptoms was approximately six months (range 1-14 months). None had been previously diagnosed as having sinusitis or received appropriate treatment. Although all were referred for evaluation of allergic rhinitis and/or asthma, approximately 1/3 were found to have neither of these conditions. Among patients who had asthma, their asthmatic symptoms were aggravated by the sinusitis. All patients eventually responded favorably to appropriate antibiotic therapy. Earlier diagnosis and appropriate therapy would have foreshortened the course of this very discomforting condition. In recent years, we have observed a marked increase in the number of patients referred with the chief complaint of "worsening allergy" and who were subsequently found to have sinusitis. Most of the patients experienced significant incapacitation for protracted periods before a correct diagnosis was made and treatment instituted. In all but a few cases, prompt and sustained improvement followed appropriate therapy. The purpose of this report is to present a retrospective review of 34 illustrative cases.
对洛杉矶儿童医院和橙县凯撒医疗机构过敏科在上一年诊断为鼻窦炎的门诊患者进行回顾发现,有34名患者存在持续的不适和虚弱症状。症状的平均持续时间约为6个月(范围为1至14个月)。此前均未被诊断为鼻窦炎或接受过适当治疗。尽管所有患者均因过敏性鼻炎和/或哮喘接受评估,但约三分之一的患者未患这两种疾病。患有哮喘的患者中,鼻窦炎会加重其哮喘症状。所有患者最终对适当的抗生素治疗反应良好。早期诊断和适当治疗本可缩短这种非常不适状况的病程。近年来,我们观察到以“过敏加重”为主诉前来就诊且随后被诊断为鼻窦炎的患者数量显著增加。大多数患者在做出正确诊断并开始治疗之前,长期存在明显的功能丧失。除少数病例外,适当治疗后均迅速且持续改善。本报告的目的是对34例典型病例进行回顾性分析。