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经鼻滥用处方氢可酮/对乙酰氨基酚导致口鼻瘘:一例报告

Intranasal abuse of prescription hydrocodone/acetaminophen results in oronasal fistula: a case report.

作者信息

Sloan Paul A, Klimkina Oksana

机构信息

Department of Anesthesiology, University of Kentucky Medical Center, Lexington, Kentucky, USA.

出版信息

J Opioid Manag. 2009 Nov-Dec;5(6):383-5. doi: 10.5055/jom.2009.0039.

DOI:10.5055/jom.2009.0039
PMID:20073413
Abstract

Opioids are becoming more common in the treatment of chronic nonmalignant pain. With increased availability of opioids for chronic pain we may expect an increased misuse of these as analgesics as well. The authors describe the case report of a young woman with chronic back pain and intranasal abuse of prescribed hydrocodone/acetaminophen who was diagnosed after presenting for hypernasal speech and foreign body in the nose. This case report highlights the need for vigilance on the part of the physician for any aberrant drug-related behaviors. Any unusual symptoms or signs such as hypernasal speech, chronic nasal infection, or unexplained foreign body sensation in the nose should be thoroughly investigated.

摘要

阿片类药物在慢性非恶性疼痛的治疗中越来越常见。随着用于慢性疼痛的阿片类药物供应增加,我们可能预计这些药物作为镇痛药的滥用情况也会增加。作者描述了一名患有慢性背痛的年轻女性的病例报告,该女性通过鼻内滥用处方的氢可酮/对乙酰氨基酚,在因鼻音过重和鼻腔内有异物就诊后被诊断出来。该病例报告强调了医生对任何异常药物相关行为保持警惕的必要性。任何不寻常的症状或体征,如鼻音过重、慢性鼻腔感染或鼻腔内无法解释的异物感,都应进行彻底调查。

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Intranasal abuse of prescription hydrocodone/acetaminophen results in oronasal fistula: a case report.经鼻滥用处方氢可酮/对乙酰氨基酚导致口鼻瘘:一例报告
J Opioid Manag. 2009 Nov-Dec;5(6):383-5. doi: 10.5055/jom.2009.0039.
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引用本文的文献

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Pain Med. 2018 May 1;19(5):955-966. doi: 10.1093/pm/pnx195.
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Intranasal hydrocodone-acetaminophen abuse induced necrosis of the nasal cavity and pharynx.鼻腔内海洛因-对乙酰氨基酚滥用导致鼻腔和咽部坏死。
Laryngoscope. 2012 Nov;122(11):2378-81. doi: 10.1002/lary.23542. Epub 2012 Sep 10.