磁共振波谱成像（1H-MRSI）和动态对比增强磁共振成像（DCE-MRI）：从炎症到前列腺癌的模式变化。
Magnetic resonance spectroscopic imaging (1H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI): pattern changes from inflammation to prostate cancer.
机构信息
Department of Urology, Sapienza University, Viale Policlinico 155, Rome, Italy.
出版信息
Cancer Invest. 2010 May;28(4):424-32. doi: 10.3109/07357900903287048.
PURPOSE
To assess (1)H-magnetic resonance spectroscopic imaging ((1)H-MRSI) and dynamic contrast-enhanced magnetic resonance (DCE-MRI) features in histologically confirmed prostatic chronic inflammation, prostatic intraepithelial neoplasia (PIN), low grade prostate cancer (LGPCa), and high grade prostate cancer (HGPCa).
MATERIALS AND METHODS
Ninety-six men were selected, who showed at histology a diagnosis of chronic inflammation (Group B), high grade (HG) PIN (Group C), or prostate cancer (LGPCa = Group D and HGPCa = Group E).
RESULTS
ANOVA analysis shows that inflammation (Group B) displays no significantly (p >.05) different choline and citrate levels when compared to HGPIN and LGPCa.
CONCLUSION
our results suggest the potential for these MR imaging techniques in the description of inflammatory and proliferative lesions inside the prostate gland.
目的
评估（1）H 磁共振波谱成像（（1）H-MRSI）和动态对比增强磁共振（DCE-MRI）在组织学证实的前列腺慢性炎症、前列腺上皮内瘤变（PIN）、低级别前列腺癌（LGPCa）和高级别前列腺癌（HGPCa）中的特征。
材料与方法
选择了 96 名男性，他们在组织学上表现为慢性炎症（B 组）、高级别（HG）PIN（C 组）或前列腺癌（LGPCa = D 组和 HGPCa = E 组）。
结果
方差分析显示，炎症（B 组）与 HGPIN 和 LGPCa 相比，胆碱和柠檬酸盐水平无显著差异（p>.05）。
结论
我们的结果表明，这些磁共振成像技术有可能描述前列腺内的炎症和增生性病变。
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