Buyukbayrak Esra Esim, Ergen Bahar, Karageyim Karsidag Ayse Yasemin, Kars Bulent, Turan Cem, Birtas Atesoglu Elif
Department of Obstetrics and Gynecology, Dr. Lutfi Kirdar Kartal Education and Research Hospital, Istanbul, Turkey.
J Matern Fetal Neonatal Med. 2010 Feb;23(2):187-9. doi: 10.3109/14767050903067329.
Essential thrombocythaemia (ET) is a disease characterized by an increased platelet count, megakaryocytic hyperplasia and a hemorrhagic or thrombotic tendency. Pregnancy in patients with ET can have a favorable outcome. However, ET has also been reported to complicate pregnancy by recurrent abortions, intrauterine death, and fetal growth retardation due to placental infarctions. ET has an unusual prevalence of intraabdominal (hepatic, portal and mesenteric) vein thrombosis, especially in young patients, which can lead to portal hypertension. There are ample cases in the literature of both essential thrombocytosis complicating pregnancy and portal hypertension complicating pregnancy, but the coincidence of both conditions appears to be unique. In this case report, we report a successful pregnancy in a patient with a prior diagnosis of essential thrombocytosis with remote secondary portal vein thrombosis and portal hypertension (PH).
原发性血小板增多症（ET）是一种以血小板计数增加、巨核细胞增生以及出血或血栓形成倾向为特征的疾病。ET患者怀孕可能有良好结局。然而，也有报道称ET会使妊娠复杂化，出现反复流产、宫内死亡以及因胎盘梗死导致的胎儿生长受限。ET患者腹腔内（肝、门静脉和肠系膜）静脉血栓形成的发生率异常高，尤其是在年轻患者中，这可能导致门静脉高压。文献中有大量原发性血小板增多症合并妊娠以及门静脉高压合并妊娠的病例，但这两种情况同时出现似乎很罕见。在本病例报告中，我们报告了一例先前诊断为原发性血小板增多症并伴有陈旧性继发性门静脉血栓形成和门静脉高压（PH）的患者成功妊娠的案例。
