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Monocyte NOTCH2 expression predicts IFN-β immunogenicity in multiple sclerosis patients.
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Janus-like effects of type I interferon in autoimmune diseases.
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Type I interferons: beneficial in Th1 and detrimental in Th17 autoimmunity.
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The role of cell type-specific responses in IFN-β therapy of multiple sclerosis.
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Excessive biologic response to IFNβ is associated with poor treatment response in patients with multiple sclerosis.
PLoS One. 2011;6(5):e19262. doi: 10.1371/journal.pone.0019262. Epub 2011 May 13.
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Gene regulatory and clinical effects of interferon β in patients with metastatic melanoma: a phase II trial.
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An overview of cytokines and cytokine antagonists as therapeutic agents.
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2
Interferons at age 50: past, current and future impact on biomedicine.
Nat Rev Drug Discov. 2007 Dec;6(12):975-90. doi: 10.1038/nrd2422.
4
Novel interferon-beta-induced gene expression in peripheral blood cells.
J Leukoc Biol. 2007 Nov;82(5):1353-60. doi: 10.1189/jlb.0507273. Epub 2007 Aug 20.
6
Peripheral blood gene expression signature mirrors central nervous system disease: the model of multiple sclerosis.
Autoimmun Rev. 2006 Oct;5(8):517-22. doi: 10.1016/j.autrev.2006.02.009. Epub 2006 Mar 23.
7
Drug Insight: interferon treatment in multiple sclerosis.
Nat Clin Pract Neurol. 2006 Jan;2(1):34-44. doi: 10.1038/ncpneuro0088.
8
Dynamics of interferon-beta modulated mRNA biomarkers in multiple sclerosis patients with anti-interferon-beta neutralizing antibodies.
J Neuroimmunol. 2006 Jul;176(1-2):125-33. doi: 10.1016/j.jneuroim.2006.03.019. Epub 2006 May 15.
9
Differential responses to IFN-alpha subtypes in human T cells and dendritic cells.
J Immunol. 2003 Nov 15;171(10):5255-63. doi: 10.4049/jimmunol.171.10.5255.
10
Genomic effects of IFN-beta in multiple sclerosis patients.
J Immunol. 2003 Sep 1;171(5):2694-702. doi: 10.4049/jimmunol.171.5.2694.

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