Studio Urologico Gallo, Department of Andrology, Naples, Italy.
J Sex Med. 2010 Mar;7(3):1269-76. doi: 10.1111/j.1743-6109.2009.01661.x. Epub 2010 Jan 14.
The role of short frenulum and the effects of frenulectomy on premature ejaculation (PE) were never investigated.
The aims of this study were to evaluate the prevalence of short frenulum in a population of patients affected by lifelong PE and to investigate the role of frenulectomy as first-line treatment for this condition.
We performed frenulectomy to patients complaining of lifelong PE in which we found the presence of a short frenulum at physical examination. We evaluated intravaginal ejaculatory latency time (IELT) and the score of a validated PE questionnaire at baseline and after frenulectomy.
We evaluated the change in mean IELT and in mean PE questionnaire score.
We found the presence of a short frenulum in 59 out of 137 (43%) subjects who came to our center complaining of lifelong PE. Mean age of study population was 38.2 years (+/-5.3 standard deviation). At baseline period, mean IELT was 1.65 minutes (+/-1.15), and mean PE questionnaire score was 15.8 (+/-2.85). No complications related to surgery occurred. Mean follow-up time was 7.3 months (+/-3.18). After frenulectomy, mean IELT was 4.11 minutes (+/-1.77), and mean PE questionnaire score was 9.85 (+/-3.2). An increase in mean IELT of 2.46 minutes (P < 0.0001) and a reduction in mean PE questionnaire symptoms score of 5.95 (P < 0.0001) were noted.
Short frenulum is a genital anomaly found in 43% of individuals affected by lifelong PE in our data set. We suggest always ruling out at physical examination the presence of a short frenulum in all patients complaining of PE and to propose frenulectomy as first-line treatment in these cases.
短系带的作用以及系带切除术对早泄（PE）的影响从未被研究过。
本研究旨在评估在患有终身性 PE 的患者人群中短系带的患病率，并探讨系带切除术作为该疾病一线治疗方法的作用。
我们对因终身性 PE 前来就诊并在体格检查中发现存在短系带的患者进行了系带切除术。我们在基线时和系带切除术后评估了阴道内射精潜伏期时间（IELT）和经过验证的 PE 问卷的评分。
我们评估了平均 IELT 和平均 PE 问卷评分的变化。
我们发现 137 名因终身性 PE 来我们中心就诊的患者中有 59 名（43%）存在短系带。研究人群的平均年龄为 38.2 岁（+/-5.3 标准差）。在基线期，平均 IELT 为 1.65 分钟（+/-1.15），平均 PE 问卷评分为 15.8（+/-2.85）。手术相关并发症未发生。平均随访时间为 7.3 个月（+/-3.18）。系带切除术后，平均 IELT 为 4.11 分钟（+/-1.77），平均 PE 问卷评分为 9.85（+/-3.2）。平均 IELT 增加 2.46 分钟（P < 0.0001），PE 问卷症状评分降低 5.95（P < 0.0001）。
短系带是我们数据集中 43%患有终身性 PE 的个体存在的一种生殖器异常。我们建议在所有因 PE 前来就诊的患者中，始终通过体格检查排除短系带的存在，并在这些情况下建议将系带切除术作为一线治疗方法。
