Clinical Sciences Research Institute, Warwick University, Clifford bridge road, Coventry, CV2 2DX, UK.
BMC Musculoskelet Disord. 2010 Jan 14;11:8. doi: 10.1186/1471-2474-11-8.
Hip replacement (arthroplasty) surgery is a highly successful treatment for patients with severe symptomatic arthritis of the hip joint. For older patients, several designs of Total Hip Arthroplasty have shown excellent results in terms of both function and value for money. However, in younger more active patients, there is approximately a 50% failure rate at 25 years for traditional implants. Hip resurfacing is a relatively new arthroplasty technique. In a recent review of the literature on resurfacing arthroplasty it was concluded that the short-term functional results appear promising but some potential early disadvantages were identified, including the risk of femoral neck fracture and collapse of the head of the femur. The aim of the current study is to assess whether there is a difference in functional hip scores at one year post-operation between Total Hip Arthroplasty and Resurfacing Arthroplasty. Secondary aims include assessment of complication rates for both procedures as well cost effectiveness.
METHODS/DESIGN: All patients medically fit for surgery and deemed suitable for a resurfacing arthroplasty are eligible to take part in this study. A randomisation sequence will be produced and administered independently. After consenting, all patients will be clinically reviewed and hip function, quality of life and physical activity level will be assessed through questionnaires. The allocated surgery will then be performed with the preferred technique of the surgeon. Six weeks post-operation hip function will be assessed and complications recorded. Three, six and 12 months post-operation hip function, quality of life and physical activity level will be assessed. Additional information about patients' out-of-pocket expenses will also be collected.
Current Controlled Trials ISRCTN33354155. UKCLRN portfolio ID 4093.
髋关节置换术（关节成形术）是治疗髋关节严重症状性关节炎患者的一种非常成功的治疗方法。对于老年患者，几种全髋关节置换术设计在功能和性价比方面都取得了优异的效果。然而，对于年轻、更活跃的患者，传统植入物在 25 年内的失败率约为 50%。髋关节表面置换术是一种相对较新的关节置换技术。在最近对髋关节表面置换术文献的综述中得出结论，短期功能结果似乎很有希望，但也发现了一些潜在的早期缺点，包括股骨颈骨折和股骨头部塌陷的风险。本研究的目的是评估全髋关节置换术和髋关节表面置换术在术后一年的功能髋关节评分是否存在差异。次要目标包括评估两种手术的并发症发生率和成本效益。
方法/设计：所有适合手术且适合髋关节表面置换术的患者均有资格参加本研究。将产生并独立管理随机序列。在同意后，所有患者将进行临床评估，并通过问卷调查评估髋关节功能、生活质量和身体活动水平。然后将根据外科医生的喜好进行分配的手术。术后 6 周评估髋关节功能并记录并发症。术后 3、6 和 12 个月评估髋关节功能、生活质量和身体活动水平。还将收集有关患者自付费用的其他信息。
当前对照试验 ISRCTN33354155。UKCLRN 投资组合 ID 4093。
