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与假孕大鼠每日催乳素激增相关的垂体催乳素浓度

Pituitary prolactin concentrations associated with daily prolactin surges in pseudopregnant rats.

作者信息

Furudate S

机构信息

Department of Laboratory Animal Science, Kitasato University School of Medicine, Kanagawa, Japan.

出版信息

Jikken Dobutsu. 1991 Jan;40(1):39-43. doi: 10.1538/expanim1978.40.1_39.

DOI:10.1538/expanim1978.40.1_39
PMID:2007433
Abstract

During pseudopregnancy (PSP) two surges of prolactin (PRL) secretion from the pituitary are observed, the nocturnal surge at dawn and the diurnal surge in the evening. An attempt was made to clarify the correlation between changes in serum and pituitary PRL concentrations on day 5-6 of PSP. During the nocturnal surge, pituitary PRL concentration decreased significantly from 0000 hr to 0300-0600 hr. On the other hand, the high pituitary PRL concentration remained unchanged during the diurnal surge from 1200 hr to 1800 hr. These findings suggest that the nocturnal and diurnal PRL surges are regulated by separate controlling mechanisms.

摘要

在假孕(PSP)期间,观察到垂体催乳素(PRL)分泌出现两次高峰,黎明时的夜间高峰和傍晚的日间高峰。本研究旨在阐明PSP第5 - 6天血清和垂体PRL浓度变化之间的相关性。在夜间高峰期间,垂体PRL浓度从00:00时到03:00 - 06:00时显著下降。另一方面,在12:00时到18:00时的日间高峰期间,垂体PRL高浓度保持不变。这些发现表明,夜间和日间PRL高峰受不同的控制机制调节。

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