硝酸甘油可增强缺氧肿瘤组织中的血管血流和药物递送：心绞痛与实体瘤的类比以及对增强渗透与滞留（EPR）效应的作用 - Suppr

Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: analogy between angina pectoris and solid tumors and enhancement of the EPR effect.

作者信息

Maeda Hiroshi

机构信息

Faculty of Pharmaceutical Sciences, Sojo University, Ikeda 4-22-1, Kumamoto 860-0082, Japan.

出版信息

J Control Release. 2010 Mar 19;142(3):296-8. doi: 10.1016/j.jconrel.2010.01.002. Epub 2010 Jan 20.

DOI:10.1016/j.jconrel.2010.01.002

PMID:20074683

Abstract

摘要

相似文献

Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: analogy between angina pectoris and solid tumors and enhancement of the EPR effect.

J Control Release. 2010 Mar 19;142(3):296-8. doi: 10.1016/j.jconrel.2010.01.002. Epub 2010 Jan 20.

Pharmacological approaches to the therapy of angina.

Adv Drug Res. 1974;9:103-34.

[The effects of intracoronary injection of nitroglycerin on the coronary circulation: evaluation using a Doppler catheter].

J Cardiol. 1992;22(2-3):367-73.

Organic nitrates in angina pectoris.

Arch Int Pharmacodyn Ther. 1972 Apr;196:Suppl 196: 25-.

Coronary vasomotion in angina at rest and effect of sublingual nitroglycerin on coronary blood flow.

Am J Cardiol. 1985 Sep 1;56(7):484-5. doi: 10.1016/0002-9149(85)90893-8.

Different effects of nitroglycerin and nitroprusside on myocardial blood flow and metabolism.

Scand J Clin Lab Invest Suppl. 1984;173:75-9.

Contrast echocardiography displays increased subendocardial perfusion after nitroglycerin administration.

J Am Soc Echocardiogr. 1997 Apr;10(3):210-4. doi: 10.1016/s0894-7317(97)70056-7.

Nitroglycerin and dipyridamole on cardiac metabolism and dynamics in a new experimental model of angina pectoris.

J Pharmacol Exp Ther. 1976 Jan;196(1):15-28.

[The effect of nitroglycerin on the regional myocardial blood flow in man (author's transl)].

Wien Klin Wochenschr. 1974 Mar 22;86(6):145-7.

[Myocardial metabolism and left ventricular pressure in angina pectoris].

Verh Dtsch Ges Kreislaufforsch. 1969;35:405-9.

引用本文的文献

Ultrasound-Induced Nitric Oxide-Propelled Nanomotor for Multimodal Theranostics of Cancer with Deep Penetration and Extended Lifetime.

Adv Sci (Weinh). 2025 Aug;12(30):e16709. doi: 10.1002/advs.202416709. Epub 2025 Jun 10.

Microfluidic Modulation of Microvasculature in Microdissected Tumors.

bioRxiv. 2024 Oct 7:2024.09.26.615278. doi: 10.1101/2024.09.26.615278.

Targeted Radium Alpha Therapy in the Era of Nanomedicine: In Vivo Results.

Int J Mol Sci. 2024 Jan 4;25(1):664. doi: 10.3390/ijms25010664.

Promoting Intratumoral Drug Accumulation by Bio-Membrane Regulated Active Targeting for Tumor Photothermal Therapy.

Int J Nanomedicine. 2023 Dec 5;18:7287-7304. doi: 10.2147/IJN.S434645. eCollection 2023.

Nitroglycerin: a comprehensive review in cancer therapy.

Cell Death Dis. 2023 May 12;14(5):323. doi: 10.1038/s41419-023-05838-5.

Drug Repurposing in Non-Small Cell Lung Carcinoma: Old Solutions for New Problems.

Curr Oncol. 2023 Jan 5;30(1):704-719. doi: 10.3390/curroncol30010055.

Thinking about Enhanced Permeability and Retention Effect (EPR).

J Pers Med. 2022 Jul 30;12(8):1259. doi: 10.3390/jpm12081259.

Approaches to Improve Macromolecule and Nanoparticle Accumulation in the Tumor Microenvironment by the Enhanced Permeability and Retention Effect.

Polymers (Basel). 2022 Jun 27;14(13):2601. doi: 10.3390/polym14132601.

Nitroglycerin-induced downregulation of AKT- and ERK1/2-mediated radiation-sensitive 52 expression to enhance pemetrexed-induced cytotoxicity in human lung cancer cells.

Toxicol Res (Camb). 2022 Mar 26;11(2):299-310. doi: 10.1093/toxres/tfac013. eCollection 2022 Apr.

Marked increase in tumor transfection with a truncated branched polymer.

J Gene Med. 2022 Jan;24(1):e3396. doi: 10.1002/jgm.3396. Epub 2021 Nov 18.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: analogy between angina pectoris and solid tumors and enhancement of the EPR effect.

作者信息

机构信息

出版信息

相似文献

引用本文的文献

文献AI研究员

用中文搜PubMed

文档翻译

Suppr 超能文献

Nitroglycerin enhances vascular blood flow and drug delivery in hypoxic tumor tissues: analogy between angina pectoris and solid tumors and enhancement of the EPR effect.

作者信息

机构信息

出版信息

相似文献

引用本文的文献