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Strategies to improve the EPR effect: A mechanistic perspective and clinical translation.
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Challenges and key considerations of the enhanced permeability and retention effect for nanomedicine drug delivery in oncology.
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To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?
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Advances in Materials Science for Precision Melanoma Therapy: Nanotechnology-Enhanced Drug Delivery Systems.
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Doxorubicin loaded thermostable nanoarchaeosomes: a next-generation drug carrier for breast cancer therapeutics.
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本文引用的文献

2
The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy.
Theranostics. 2020 Jun 25;10(17):7921-7924. doi: 10.7150/thno.49577. eCollection 2020.
3
To exploit the tumor microenvironment: Since the EPR effect fails in the clinic, what is the future of nanomedicine?
J Control Release. 2016 Dec 28;244(Pt A):108-121. doi: 10.1016/j.jconrel.2016.11.015. Epub 2016 Nov 18.
4
Principles of nanoparticle design for overcoming biological barriers to drug delivery.
Nat Biotechnol. 2015 Sep;33(9):941-51. doi: 10.1038/nbt.3330.
5
EPR: Evidence and fallacy.
J Control Release. 2014 Sep 28;190:451-64. doi: 10.1016/j.jconrel.2014.03.057. Epub 2014 Apr 30.
7
Markedly enhanced permeability and retention effects induced by photo-immunotherapy of tumors.
ACS Nano. 2013 Jan 22;7(1):717-24. doi: 10.1021/nn305011p. Epub 2012 Dec 18.
10
Tumor delivery of macromolecular drugs based on the EPR effect.
Adv Drug Deliv Rev. 2011 Mar 18;63(3):131-5. doi: 10.1016/j.addr.2010.03.011. Epub 2010 Mar 18.

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