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一层吻合术:显微外科与放大镜辅助。

One-layer vasovasostomy: microsurgical versus loupe-assisted.

机构信息

Department of Urology, College of Medicine, CHA University, Bundang CHA Hospital, Gyeonggi, South Korea.

出版信息

Fertil Steril. 2010 Nov;94(6):2308-11. doi: 10.1016/j.fertnstert.2009.12.013. Epub 2010 Jan 13.

Abstract

OBJECTIVE

To compare the outcomes of microsurgical versus loupe-assisted technique for vasectomy reversal.

DESIGN

Retrospective comparative study with randomization.

SETTING

University hospital male infertility clinic.

PATIENT(S): Fifty men with obstructive azoospermia after vasectomy.

INTERVENTION(S): One-layer vasovasostomy with microscope (group I) or optical loupe (group II).

MAIN OUTCOME MEASURE(S): Patency, pregnancy, operation time, postoperative stricture.

RESULT(S): Mean operation time was 106.4±10.3 minutes in group I and 78.3±5.7 minutes in group II, showing a statistically significant difference. Analysis of semen sampled from men, who succeeded in getting vasal patency, was performed finally at the sixth month after surgery and showed sperm concentrations of 21.5 million/mL and 20.7 million/mL and sperm motilities of 32.5% and 30.8% in groups I and II, respectively, without a statistical significance. Patency rates were 96% (24 out of 25) in group I and 72% (18 out of 25) in group II, showing a statistically significant difference. Pregnancy rates were 40% (10 out of 25) in group I and 28% (7 out of 25) in group II. There was no statistically significant difference in pregnancy rate between the two groups. Postoperative vasal stricture occurred in four patients, all of them from group II. There was no operation-related complication, such as hematoma or wound infection.

CONCLUSION(S): Microscopic technique yielded a higher patency rate than loupe-assisted technique, possibly by reducing the chance of postoperative vasal stricture.

摘要

目的

比较显微镜下与光学助视器辅助技术在输精管复通术中的效果。

设计

随机对照的回顾性研究。

设置

大学医院男性不育症诊所。

患者

50 例输精管结扎术后梗阻性无精子症患者。

干预

显微镜下(I 组)或光学助视器(II 组)行单层端端吻合术。

主要观察指标

通畅率、妊娠、手术时间、术后狭窄。

结果

I 组手术时间平均为 106.4±10.3 分钟,II 组为 78.3±5.7 分钟,差异有统计学意义。对成功获得输精管通畅的男性进行精液分析,术后第 6 个月,I 组精子浓度为 2150 万/ml,精子活力为 32.5%;II 组分别为 2070 万/ml 和 30.8%,差异无统计学意义。I 组通畅率为 96%(24/25),II 组为 72%(18/25),差异有统计学意义。I 组妊娠率为 40%(10/25),II 组为 28%(7/25),差异无统计学意义。术后发生 4 例吻合口狭窄,均来自 II 组。无手术相关并发症,如血肿或伤口感染。

结论

显微镜下技术的通畅率高于光学助视器辅助技术,可能降低了术后吻合口狭窄的发生概率。

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