胎盘内绒毛膜癌所致母胎输血

[Fetomaternal hemorrhage caused by intraplacental choriocarcinoma].

作者信息

Touboul C, Faivre E, Boithias C, Mass A-E, Senat M-V, Fernandez H, Deffieux X

机构信息

UMR-S0782, service de gynécologie-obstétrique, hôpital Antoine-Béclère, université Paris-Sud, 157, rue de la Porte-de-Trivaux, 92140 Clamart, France.

出版信息

J Gynecol Obstet Biol Reprod (Paris). 2010 Apr;39(2):156-8. doi: 10.1016/j.jgyn.2009.10.008. Epub 2010 Jan 13.

DOI:10.1016/j.jgyn.2009.10.008

PMID:20074866

Abstract

A male infant was born at 41 weeks' gestation to a 34-year-old primiparous woman after an uneventful pregnancy. Physical examination showed extreme paleness. Fetal hemoglobin was 7.6g/dl and Kleihauher exam revealed fetomaternal hemorrhage. Pathology revealed in situ intraplacental choriocarcinoma. Serum human chorionic gonadotrophin level was undetectable 1 month after the delivery both in woman and in newborn. We suggest that a pathological examination of the placenta should be performed in any case of fetomaternal hemorrhage in order to avoid misdiagnosis of intraplacental choriocarcinoma.

摘要

一名男婴在孕41周时出生，其母亲为一名34岁的初产妇，孕期平顺。体格检查显示极度苍白。胎儿血红蛋白为7.6g/dl，Kleihauher检查显示胎儿-母体出血。病理检查显示胎盘原位绒毛膜癌。产后1个月，母亲和新生儿的血清人绒毛膜促性腺激素水平均检测不到。我们建议，对于任何胎儿-母体出血的情况，均应进行胎盘病理检查，以避免胎盘内绒毛膜癌的误诊。