Outpatient Treatment Center PsyQ, Rotterdam, The Netherlands; Institute of Psychology, Erasmus University Rotterdam, The Netherlands.
J Anxiety Disord. 2010 Mar;24(2):284-9. doi: 10.1016/j.janxdis.2009.12.005. Epub 2009 Dec 22.
The present study examined a hierarchical model for the relationships between general and specific vulnerability factors and symptom manifestations of generalized anxiety disorder (GAD). A clinical sample of patients with GAD (N=137) completed a set of self-report questionnaires for measuring neuroticism, extraversion, intolerance of uncertainty, metacognitive beliefs, and symptoms of generalized anxiety (i.e., worry) and depression. A bootstrapping analysis yielded support for a model in which the relation between the general vulnerability factor of neuroticism and symptoms of GAD were mediated by the specific vulnerability factors of intolerance of uncertainty and negative metacognitions. Implications for the classification and treatment of GAD are discussed.
本研究考察了一般和特定脆弱性因素与广泛性焦虑障碍（GAD）症状表现之间关系的层级模型。一个患有 GAD 的临床样本（N=137）完成了一组用于测量神经质、外向性、不确定性容忍度、元认知信念以及广泛性焦虑（即担忧）和抑郁症状的自我报告问卷。自举分析支持了这样一个模型，即神经质这一一般脆弱性因素与 GAD 症状之间的关系是由不确定性容忍度和消极元认知这两个特定脆弱性因素中介的。讨论了对 GAD 的分类和治疗的影响。
