Mayo Medical School, Mayo Clinic, 200 SW First Street, Rochester, MN 55905, USA.
AJNR Am J Neuroradiol. 2010 Jun;31(6):1103-5. doi: 10.3174/ajnr.A1988. Epub 2010 Jan 14.
The perimesencephalic pattern of SAH as seen on unenhanced CT is associated with significantly better outcomes when compared to an aneurysmal pattern of SAH. The aim of this study was to determine the degree of inter- and intraoberver agreement for characterization of the NAPH as seen on unenhanced CT.
We retrospectively reviewed the CT scans of 37 patients with spontaneous SAH, all of whom had undergone CT within 24 hours of onset of headache symptoms. All patients had undergone conventional cerebral angiography to confirm or exclude aneurysms or other vascular pathology. All 37 cases were angiographically confirmed nonaneurysmal SAHs. Four readers with neuroradiology subspecialty training independently evaluated CT images to characterize the hemorrhage pattern as compatible with the well-described NAPH. Each reader performed a second reading session blinded to the initial readings. The first and second sets of readings were performed approximately 4 months apart. Inter- and intraobserver agreement for characterization of the NAPH was determined by using the kappa statistic.
Of the 37 angiographically confirmed nonaneurysmal SAHs, there was unanimous agreement as to the hemorrhage pattern in 29 (78%) cases and disagreement in 8 (22%) cases. Overall, intraobserver agreement was good (kappa = 0.80). Interobserver agreement was also good (kappa = 0.79).
Overall, inter- and intraobserver agreement for the NAPH was good. There was, however, a level of disagreement among observers, thus suggesting that clinicians should be cautious when deciding whether to pursue follow-up imaging.
与动脉瘤性蛛网膜下腔出血(SAH)的模式相比,未增强 CT 上见到的围脑周围性 SAH 模式与更好的预后显著相关。本研究的目的是确定在未增强 CT 上观察到的 NAPH 的特征在观察者间和观察者内的一致性程度。
我们回顾性地分析了 37 例自发性 SAH 患者的 CT 扫描,所有患者均在头痛症状发作后 24 小时内进行了 CT 检查。所有患者均进行了常规脑血管造影以确认或排除动脉瘤或其他血管病变。所有 37 例均经血管造影证实为非动脉瘤性 SAH。4 名具有神经放射学亚专业培训的读者独立评估 CT 图像,以确定出血模式与描述明确的 NAPH 相符。每位读者在盲法下进行第二次阅读。第一次和第二次阅读大约相隔 4 个月。通过kappa 统计确定特征描述 NAPH 的观察者间和观察者内的一致性。
在 37 例经血管造影证实的非动脉瘤性 SAH 中,29 例(78%)病例的出血模式一致,8 例(22%)病例的出血模式不一致。总体而言,观察者内一致性良好(kappa=0.80)。观察者间一致性也很好(kappa=0.79)。
总体而言,NAPH 的观察者间和观察者内的一致性良好。然而,观察者之间存在一定程度的不一致,因此建议临床医生在决定是否进行随访成像时应谨慎。