Department of Dermatology, Hôpital Henri Mondor, Créteil, France.
Curr Opin Infect Dis. 2010 Apr;23(2):111-8. doi: 10.1097/QCO.0b013e328336821b.
In industrialized countries, epidemics of scabies are mainly described within families or in institutions such as healthcare settings. Control of institutional scabies is associated with a considerable working and economic burden, but guidelines for the management are scarce.
The prevalence of institutional scabies is probably underestimated. Identified risk factors for institutional scabies outbreaks include the institution type, extensive physical contact with patients and movement of patients, the existence of crusted scabies, a long diagnostic delay and failures in implementation of infection control or treatment plans.Atypical clinical features (hyperinfestation, scabies in the elderly or in children) may be misdiagnosed. Control of institutional scabies outbreaks relies on prompt recognition of the index case, constitution of an outbreak management team, determination of the extent of the outbreak and risk factors for spread, immediate implementation of infection control practices, adequate education of all involved persons, simultaneous treatment of cases and of all exposed individuals and concomitant environmental disinfection. Prolonged surveillance is imperative to eradicate scabies.
The inclusion of institutionalized patients in randomized controlled trials would be beneficial as present data concerning scabicide effectiveness are obtained from trials that recruited individual participants and do not take into account a global strategy.
在工业化国家,疥疮的流行主要发生在家庭或医疗机构等机构中。机构性疥疮的控制与相当大的工作和经济负担有关,但管理指南却很少。
机构性疥疮的流行率可能被低估。机构性疥疮暴发的危险因素包括机构类型、与患者的广泛身体接触和患者的流动、结痂性疥疮的存在、诊断延迟时间长以及感染控制或治疗计划的实施失败。不典型的临床特征(过度感染、老年人或儿童的疥疮)可能会被误诊。机构性疥疮暴发的控制依赖于及时识别索引病例,组建暴发管理团队,确定暴发的范围和传播的危险因素,立即实施感染控制措施,对所有相关人员进行充分的教育,同时治疗病例和所有接触者,并进行环境消毒。进行长期监测对于消灭疥疮至关重要。
将住院患者纳入随机对照试验将是有益的,因为目前关于杀疥药物疗效的数据是从招募个体参与者的试验中获得的,并没有考虑到全面的策略。