Kourouni Vasiliki, Verran Callum D, White Jonathan P E, Chandler David J
Dermatology Department, Brighton General Hospital, University Hospitals Sussex NHS Foundation Trust, Brighton, UK.
Department of Global Health & Infection, Brighton and Sussex Medical School, Brighton, UK.
Drugs Aging. 2025 Jun 13. doi: 10.1007/s40266-025-01219-z.
Scabies is a common and disabling ectoparasitic infestation of the skin that can clinically present in 'classical' or 'crusted' forms. Diagnosis can often be made on the basis of clinical history and careful dermoscopic examination of the skin. The International Alliance for the Control of Scabies (IACS) diagnostic criteria can support the diagnosis and management of patients with suspected scabies. Older adults are a vulnerable population; the clinical presentation of scabies can be atypical in this group and treatment can be challenging. Institutional scabies outbreaks, such as in care homes, are typically challenging to identify and, therefore, subject to diagnostic delay. These outbreaks are hard to control and an important source of morbidity, requiring simultaneous treatment of those affected, which can be complicated and time consuming. The management of scabies outbreaks involves repeated, contemporaneous (if multiple individuals) treatments with topical scabicide applications to the whole body, with decontamination of the environment(s). In some situations, topical treatment may be inappropriate and delay effective treatment.
疥疮是一种常见且使人衰弱的皮肤外寄生虫感染,临床上可表现为“经典型”或“结痂型”。通常可根据临床病史及对皮肤进行仔细的皮肤镜检查来做出诊断。国际疥疮控制联盟(IACS)的诊断标准有助于支持对疑似疥疮患者的诊断和管理。老年人是弱势群体;疥疮在该群体中的临床表现可能不典型,治疗也颇具挑战性。机构内疥疮暴发,如在养老院,通常难以识别,因此会出现诊断延迟。这些暴发难以控制,是发病的一个重要来源,需要对受影响者同时进行治疗,这可能很复杂且耗时。疥疮暴发的管理包括对全身反复同时(如果是多个个体)应用外用杀疥剂进行治疗,并对环境进行消毒。在某些情况下,局部治疗可能不合适,会延误有效治疗。