Department of Ophthalmology, Institute of Vision Research, Yonsei University College of Medicine, Gangnam Severance Hospital, Seoul, Republic of Korea.
Eye (Lond). 2010 Jul;24(7):1273-8. doi: 10.1038/eye.2009.332. Epub 2010 Jan 15.
To evaluate the relationship of axial length (AXL), intraoperatively assessed posterior vitreous detachment (PVD) status, and surgical outcomes of diabetic vitrectomy.
Retrospective, consecutive case series. Clinical records were reviewed for 115 eyes (50 males, 65 females) with more than a 6-month follow-up who underwent diabetic vitrectomy from a single surgeon. Thirty-three eyes had vitreous haemorrhage, 37 had tractional retinal detachment (TRD) threatening the macula, 43 had TRD involving the macula, and two had neovascular glaucoma. AXL was measured preoperatively by ultrasonography, and PVD status was classified intraoperatively: broad vitreo-retinal adhesion as no PVD, PVD at the macular area with attachment at the disc as incomplete PVD, and complete PVD.
Forty-four eyes had no PVD, 23 had incomplete PVD, and 48 had complete PVD. A majority of the no PVD group had macula off TRD (97.7%), whereas vitreous haemorrhage (68.7%) predominated in the complete PVD group. Longer AXLs were noted in the complete PVD group compared with the no PVD and incomplete PVD groups (ANOVA in three groups P=0.0001). Univariate analysis showed that AXL had an influence on anatomical success (P=0.02). Multiple logistic regression analysis yielded that PVD status is a significant predictor of the final best corrected visual acuity (BCVA)>20/100, and BCVA>20/40 (P=0.01, P=0.02).
Intraoperatively assessed PVD status is a prognostic factor for functional outcomes of diabetic vitrectomy. Shorter AXL was associated with lesser PVD. In eyes with a lack of PVD, careful timing and decision of surgery are mandatory.
评估眼轴长度(AXL)、术中评估的后玻璃体脱离(PVD)状态与糖尿病性玻璃体切除术的手术结果之间的关系。
回顾性、连续病例系列研究。对单名外科医生进行的糖尿病性玻璃体切除术的 115 只眼(50 名男性,65 名女性)进行了临床记录回顾,随访时间超过 6 个月。33 只眼有玻璃体积血,37 只眼有牵拉性视网膜脱离(TRD)并累及黄斑,43 只眼有累及黄斑的 TRD,2 只眼有新生血管性青光眼。术前通过超声测量 AXL,并术中对 PVD 状态进行分类:广泛的玻璃体视网膜粘连为无 PVD,黄斑区有 PVD 但与视盘附着为不完全 PVD,完全 PVD。
44 只眼无 PVD,23 只眼不完全 PVD,48 只眼完全 PVD。无 PVD 组大多数为黄斑区脱离的 TRD(97.7%),而完全 PVD 组则以玻璃体积血(68.7%)为主。与无 PVD 和不完全 PVD 组相比,完全 PVD 组的 AXL 更长(三组 ANOVA,P=0.0001)。单变量分析表明,AXL 对解剖学成功有影响(P=0.02)。多元逻辑回归分析显示,PVD 状态是最终最佳矫正视力(BCVA)>20/100 和 BCVA>20/40 的显著预测因子(P=0.01,P=0.02)。
术中评估的 PVD 状态是糖尿病性玻璃体切除术功能结果的预后因素。较短的 AXL 与较少的 PVD 相关。在缺乏 PVD 的眼中,必须谨慎选择手术时机和决策。