Zhang Li, Xu Ai-Qian, Yan Bing-Yu
Shandong Provincial Center for Disease Control and Prevention, Jinan 250014, Shandong, China.
Zhongguo Yi Miao He Mian Yi. 2009 Apr;15(2):159-62.
To reveal the hepatitis B vaccine (HepB) coverage in the population of 1-59 years old in Shandong province and provide evidence for improving the strategy for hepatitis B control.
A cross-section survey was conducted among the population aged 1-59 year-old in Shandong province in 2006. The study population was selected by multi-stage randomly sampling method and HepB immunization history was obtained by immunization record (for children 1-14 years old) or recall. Weighted coverage rates were calculated.
The weighted complete HepB coverage in the population 1-59 years old was [27.07%95% Confidence Internal (CI) 22.56%-31.59%] in Shandong province and was 99.66% (95% CI 99.72-100.00%), 89.95% (95% CI 87.69%-92.20%) and 13.21% (95% CI 7.78%-18.65%) in the age group of 1-4 years old, 5-14 years old and 15-59 years old, respectively. The complete HepB coverage varied significantly in the age groups (P < 0.05). No differences were found between the males and females, the rural and urban inhabitants, and among the population living in the eastern, western and central areas (P > 0.05). The weighted timely birth-dose HepB coverage was 65.41% (95% CI 55.56%-75.25%) in the children 1 to 14 years of age, which declined with age and reached the highest level in the children aged 1 year (93.07%; 95% CI 88.43%-97.70%).
A HepB catch-up campaign should be conducted in the elder children in Shandong province and further efforts should be made to improve HepB coverage among the high risk population for enhancement of hepatitis B control.
了解山东省1-59岁人群乙型肝炎疫苗(HepB)接种率,为完善乙肝防控策略提供依据。
2006年对山东省1-59岁人群进行横断面调查。采用多阶段随机抽样方法选取研究对象,通过免疫记录(1-14岁儿童)或回忆调查获取HepB免疫史,计算加权接种率。
山东省1-59岁人群加权全程HepB接种率为[27.07%,95%可信区间(CI)22.56%-31.59%],1-4岁、5-14岁和15-59岁年龄组分别为99.66%(95%CI 99.72-100.00%)、89.95%(95%CI 87.69%-92.20%)和13.21%(95%CI 7.78%-18.65%)。全程HepB接种率在各年龄组间差异有统计学意义(P<0.05)。男女之间、城乡居民之间以及东部、西部和中部地区人群之间差异无统计学意义(P>0.05)。1-14岁儿童加权及时首剂HepB接种率为65.41%(95%CI 55.56%-75.25%),随年龄增长而下降,1岁儿童最高(93.07%;95%CI 88.43%-97.70%)。
山东省应针对大龄儿童开展HepB查漏补种工作,并进一步提高高危人群HepB接种率,以加强乙肝防控。